慢性浅表性胃炎脾虚证消化吸收障碍亚型的临床分析  

Clinical Analysis of Digestive and Absorptive Disturbance Subtype in Chronic Superficial Gastritis Patients with Spleen Deficiency Syndrome

作　　者：林传权[1] 王桂香[1] 李茹柳[1] 陈玉龙[1] 劳绍贤[1] 陈蔚文[1,2] 

机构地区：[1]广州中医药大学脾胃研究所,广东广州510405 [2]上海市高校中医内科学E研-究院,上海201203

出　　处：《广州中医药大学学报》2008年第6期488-491,共4页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金重大研究计划重点项目(编号:90209004);广东省自然科学基金重点项目(编号:05102323);上海市教育委员会E-研究院建设计划项目(编号:E03008)

摘　　要：【目的】分析慢性浅表性胃炎脾虚证消化吸收功能障碍亚型患者(简称脾虚证亚型)证候特点。【方法】选择40例慢性浅表性胃炎脾虚证亚型患者临床资料为研究组,以103例慢性浅表性胃炎脾胃湿热证患者(脾胃湿热证)为对照组,比较脾虚证亚型与脾胃湿热证相同症状指标出现频率的差异,并分析脾虚证亚型病情轻重程度。【结果】脾虚证亚型出现频率超过50%的症状有舌淡苔白、脉细弱、体倦乏力、食后腹胀、纳呆食少、胃脘胀满、脘腹疼痛、神疲懒言、嗳气、口淡等;脾胃湿热证出现频率超过50%的症状有舌苔黄腻、脉滑或濡、胃脘胀满、脘腹疼痛、口干、嗳气、食后腹胀等。脾虚证亚型食后腹胀、纳呆食少、神疲懒言、消瘦的出现频率(分别为82.5%、77.5%、52.5%和47.5%)明显高于脾胃湿热证(分别为50.5%、46.6%、15.5%和18.4%),两组比较差异均有显著性意义(P<0.001)。脾虚证亚型以轻、中度慢性胃炎患者居多,重度较少。【结论】脾虚证消化吸收障碍亚型临床上是客观存在的,脾虚亚型患者消化吸收功能不良、营养代谢障碍等有其特定的临床症状和基因背景。Objective To analyze the symptoms and signs of digestive and absorptive disturbance subtype （ spleen deficiency subtype） in chronic superficial gastritis （CSG） patients with spleen deficiency syndrome. Methods The clinical data in 40 CSG patients with spleen deficiency subtype was analyzed, and 103 CSG patients with spleen-stomach damp-heat syndrome served as the control. The differences of symptom ranging were also discussed between the two groups. Results Symptoms and signs with the incidence over 50% in spleen deficiency subtype were pale tongue with white coating, thready and weak pulse, lassitude, postprandial abdominal distension, loss of appetite, epigastric flatulence, abdominal pain, mental lassitude and disinclination to talk, belching and tastelessness in the mouth. Symptoms and signs with the incidence over 50% in spleen-stomach damp-heat syndrome were yellowish and greasy coating, smooth or soft pulse, epigastric flatulence, abdominal pain, dry mouth, belching and postprandial abdominal distension. The incidence of postprandial abdominal distension, loss of appetite, mental lassitude and emaciation was 82.5%, 77.5%, 52.5% and 47.5% respectively in spleen deficiency subtype, and were 50.5%, 46.6%, 15.5% and 18.4% respectively in spleen-stomach damp-heat syndrome. The differences of the above indexes were significant between the two groups （ P 〈 0. 001 ）. Spleen deficiency subtype was most frequently seen in mild and moderate chronic gastritis, less frequently seen in the severe chronic gastritis. Conclusion There exists the digestive and absorptive disturbance subtype （spleen deficiency subtype ） in spleen deficiency syndrome, which presents the specific symptoms of digestive and absorptive disturbance and nutritional metabolic disturbance, and special genetic features.

关 键 词：脾虚证 脾胃湿热证 证候分析 

分 类 号：R259.733[医药卫生—中西医结合]