人工栽培的南方红豆杉化学成分研究(Ⅲ)(英文)  

Studies on chemical constituents of planted Taxus mairei(Ⅲ)

作　　者：陈雪英[1] 梁敬钰[1] 

机构地区：[1]中国药科大学天然药化教研室,江苏南京210009

出　　处：《药学学报》2008年第12期1205-1207,共3页Acta Pharmaceutica Sinica

摘　　要：从人工栽培的南方红豆杉全株乙醇提取物的氯仿萃取部位通过反复硅胶和凝胶柱层析分离得到4个化合物,采用波谱解析(IR,ESI-MS,1HNMR和13C NMR)等方法确定了其结构,4个化合物分别鉴定为taxamairin K(1),2α,4α-dideacetoxy-7β-benzoyloxy-5β,20-epoxy-9α,10β,13α,15-tetrahydroxy-11(15→1)abeotaxa-11-ene(2),7β-xylosyl-taxol(3),10-deacetoxy-7-xylosyl-taxol(4),其中化合物1为新化合物。From the chloroform-soluble fraction of the ethanol extracts of the whole plant of Taxus chinensis var. mairei （Lemee et Levl ）, four compounds were isolated by using repeated column chromatography on silica gel and Sephadex LH-20. Based on spectroscopic data （UV, IR, ESI-MS, ^1H NMR and ^13C NMR）, the compounds were identified as taxamairin K （1）, 2α, 4α-dideacetoxy-7β- benzoyloxy-5β,20-epoxy-9α, 10β, 13α, 15-tetrahydroxy-11 （ 15→1 ） abeotaxa-11 -ene （2）, 7β-xylosyl-taxol （3）, 10-deacetoxy-7-xylosyl-taxol （4）. Among them, taxamairin K is a new compound.

关 键 词：南方红豆杉 taxamairin K 人工栽培 

分 类 号：R284.1[医药卫生—中药学]