干扰素两种方案治疗丙型肝炎效果观察  

Effect of different schemes of interferon therapy on hepatitis C.

作　　者：孙焱[1] 王豪[1] 房继莲[1] 张晶芬 陶其敏[1] 冯百芳[1] 

机构地区：[1]北京医科大学人民医院盯病研究所,长春市第一汽车集团公司职工医院

出　　处：《临床肝胆病杂志》1998年第1期54-56,共3页Journal of Clinical Hepatology

摘　　要：本文对急慢性丙型肝炎１３１例患者，应用两种干扰素方案治疗。在初次干扰素治疗时，早期、大量、连续给药，并延长疗程至半年以上，对于急性丙肝患者血清ＡＬＴ的复常率可提高至８３．３％，ＨＣＶＲＮＡ阴转嵚剩福常常ィ欢杂诼员危粒蹋缘母闯Ｂ饰福叮罚ィ龋茫郑遥危烈踝剩罚常常ァ４私峁崾荆杂诩毙员危瑣早期大剂量干扰素治疗，可使病毒血症早期消失，可能有助于病毒的彻底清除和减少病毒对肝脏的损害；1 31 patients with acute and chronic hepatitis C were investigated for the effect of two schemes ofinterferon therapy.Our result indicated that giving interferon daily for a period of 4 weeks in the beginning of the treatment could markedly improve the respondingrate in patients with acute hepatits C as defined by the clearance of HCV RNA. In addition , prolonging thetreatment duration to as long as 6 months could also be benefit.

关 键 词：干扰素 丙型肝炎 药物疗法 

分 类 号：R512.630.5[医药卫生—内科学]