MSCT对药物性肺损害的诊断价值  

Diagnostic value of MSCT to drug-induced pulmonary lesions

作　　者：明路民[1] 闫呈新[1] 于富华[2] 陈松果[1] 于台飞[3] 

机构地区：[1]泰山医学院附属医院影像中心,山东泰安271000 [2]潍坊医学院,山东潍坊261053 [3]山东省医学影像学研究所,山东济南250021

出　　处：《医学影像学杂志》2008年第11期1251-1255,共5页Journal of Medical Imaging

摘　　要：目的:通过对照分析药物性肺损害的CT表现与病理改变,探讨CT尤其是HRCT对本病的的诊断价值。方法:回顾性分析诊断明确的13例药物性肺损害的肺部CT或HRCT表现,确认临床用药史并与病理结果对照。本组男9例,女4例。年龄22～72岁;平均年龄59.1岁。结果:本组药物性肺损害CT表现为间质性肺炎3例、间质性纤维化4例、嗜酸性粒细胞肺炎1例、闭塞性细支气管炎伴机化性肺炎2例、肺梗死1例、急性肺水肿1例、过敏性肺炎1例。结论:①药物性肺损害的影像表现是非特异性的;②CT尤其是HRCT可以清楚的显示肺损害的病理改变,并能追踪观察病变的发展变化,对临床制定或修改治疗方案有重要的提示或指导意义。Objective：Through the control of drug-induced pulmonary lesion and CT findings of the pathological changes, particularly on HRCT of the disease in the diagnostic value. Methods： CT or HRCT findings in 13 patients with diagnosis explicit drug-induced pulmonary lesion were retrespectively analyzed, including 9 males and 4 females with the age of 22 - 72 years （mean 59.1 years）. And the history of drug use and pathological findings were controlled. Results： The group of drug-induced pulmonary lesion CT findings of three cases of interstitial pneumonia, four cases of interstitial fibrosis, one case of acidophilia granular cell pneumonia, bronchiolitis obliterans organizing pneumonia two cases, one case of pulmonary infarction. One case of acute pulmonary edema, one case of allergic pneumonia. Conclusion：Image finding of drug-induced pulmonary lesion was non-specific; and CT especially HRCT can clearly show that the pulmonary lesion to the pathological changes, and to track changes in the development of lesions observed, develop or modify the clinical treatment has important suggestion or guidance significance.

关 键 词：药物性肺损害 体层摄影术 X线计算机 

分 类 号：R561[医药卫生—呼吸系统] R814.42[医药卫生—内科学]