甲亢患者骨矿物含量与血清PTH、BGP和CT的关系  

The Relationship Between Bone Mineral Density and Serum TH,BGP and CT Levels in The Relationship between Bone Mineral Density and Serum PTH,BGP and CT Levels in Patients with Hyperthyroidism

作　　者：张雪峰[1] 崔凯[1] 姜秋菊[1] 李春辉[1] 

机构地区：[1]北华大学附属医院,吉林吉林132011

出　　处：《标记免疫分析与临床》2008年第6期380-381,共2页Labeled Immunoassays and Clinical Medicine

摘　　要：为探讨甲亢患者骨矿物含量(BMD)与血清甲状旁腺激素(PTH)、骨钙素(BGP)和降钙素(CT)的关系,以167例甲亢患者为甲亢组,58名正常人为对照组,测定两组BMD和用RIA测定血清BGP、PTH、CT。结果表明,甲亢组的BMD(0.52±0.21g/cm2)和CT(70.3±12.9ng/L)比正常组(0.79±0.36g/cm2,102.7±27.4ng/L)下降(P<0.01)。甲亢组血清PTH(30.4±9.6ng/L)和BGP(12.6±4.1μg/L)比对照组(22.8±8.1ng/L,6.3±1.1μg/L)升高(P<0.01)。本文提示,甲亢患者的BMD与血清PTH、BGP、CT水平有关。To explore the relationship between the bone mineral density （BMD） and serum PTH, BGP and CT levels in patients with hyperthyroidism. The serum levels of BGP, CT and PTH in 167 patients with hyperthyroidism and 58 normal controls were determined by RIA. The results showed that the ser- um CT levels and BMD in patients with hyperthyroidism were significantly lower than those in the control group （P 〈 0.01 ）. The serum levels of PTH and BGP in patients were significantly higher than those in the control group （ P 〈 0.01 ）. The BMD in patients with hyperthyroidism was related to the serum levels of PTH, BGP and CT.

关 键 词：甲亢 甲状旁腺激素 骨钙素 降钙素 骨矿物含量 

分 类 号：R581.1[医药卫生—内分泌]