功能性消化不良患者焦虑、抑郁状况与生活质量的相关性研究  

The study of relationship between anxiety,depression and quality of life in patients with functional dyspepsia

作　　者：王美峰[1] 林琳[1] 张红杰[1] 林征[1] 朱芬芬[1] 周丽荣[1] 

机构地区：[1]南京医科大学第一附属医院消化科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2008年第12期1677-1679,共3页Journal of Nanjing Medical University(Natural Sciences)

基　　金：国家重点基础研究发展计划(973计划)(2006CB503908)

摘　　要：目的:探讨功能性消化不良(FD)患者焦虑、抑郁状况以及与生活质量的关系。方法:采用汉化版简明健康调查量表(SF-36)和ZUNG焦虑自评量表(SAS)、抑郁自评量表(SDS)对78例符合罗马Ⅲ标准的FD患者的心理状况和生活质量进行评分。结果:FD患者存在明显的焦虑和抑郁心理,与国内常模相比,SDS、SAS分值差异均有显著性(47±11vs42±11,42±11vs37±13,P<0.01);FD患者的生活质量明显下降,与中国常模相比,生理功能、生理职能、躯体疼痛、活力、情感职能、精神健康、社会功能、和总体健康8个维度差异均有显著性(P<0.01);SF-36各维度分值均与SAS、SDS分值呈负相关(P<0.01)。结论:FD患者存在明显的焦虑、抑郁心理,其生活质量显著降低,生活质量与焦虑、抑郁情绪密切相关。Objective：To study relationship between anxiety,depression and quality of life in patients with functional dyspepsia （FD）. Methods：Total of 78 patients with FD （according to Rome Ⅲ criteria）were evaluated by Zung＇s self-rating anxiety scales （SAS）and Zung＇s self-rating depression scales （SDS） and Chinese version of the MOS 36-item short form healthy survey（SF-36）. Results：The SDS and SAS scores were significantly higher in FD patients than those in Chinese normal. The SF-36 scores in all dimensions including physical functioning, role of physical, pain, vitality, role of emotional, mental health, social functioning and general health in FD patients were significantly lower than that in Chinese normal. The SF-36 scores in all dimensions had a negative association with SDS and SAS scores （P 〈 0.01）. Conclusion：There was close relationship between anxiety,depression state and quality of life in FD patients.

关 键 词：功能性消化不良 焦虑 抑郁 生活质量 

分 类 号：R195.4[医药卫生—卫生统计学]