Study the dynamic effects of exercise on IRS-2 content and tyrosine phosphorylation in skeletal muscle of rats  

作　　者：李永春 

机构地区：[1]Liaoning Advanced Police Officer College

出　　处：《辽宁师范大学学报（自然科学版）》2008年第4期500-502,共3页Journal of Liaoning Normal University:Natural Science Edition

基　　金：辽宁省教育厅科学技术研究项目(20060474)

摘　　要：To explore the dynamic effects of exercise on IRS-2 protein content and tyrosine phosphorylation in DM rats,Sixty SD rats were divided into six groups: normal control group(NC)、diabetes mellitus group(DMC) and exercise group.The exercise groups exercised for different periods of time.The content and tyrosine phosphorylation of IRS-2 protein were measured by Western bolt analysis.Result showed that contents of IRS-2 protein in 60,120,180 min groups were enhanced up to 19.0%,22.4% and 17.2%(P<0.01) respectively,and the tyrosine phosphorylation of IRS-2 protein in 60,120,180 min group enhanced up to 43.1%,80.4% and 53%(P<0.01) respectively,compared with the DMC group.We concluded that that the contents and the tyrosine phosphorylation of IRS-2 protein had obvious time trait after exercise.To explore the dynamic effects of exercise on IRS-2 protein content and tyrosine phosphorylation in DM rats, Sixty SD rats were divided into six groups： normal control group（NC）,diabetes mellitus group（DMC） and exercise group. The exercise groups exercised for different periods of time. The content and tyrosine phosphorylation of IRS-2 protein were measured by Western bolt analysis. Result showed that contents of IRS-2 protein in 60,120, 180 mingroups were enhanced up to 19.0% ,22.4% and 17.2% （P〈0.01） respectively, and the tyrosine phosphorylation of IRS-2 protein in 60,120,180 min group enhanced up to 43.1% 80.4% and 53% （P〈0. 01） respectively, compared with the DMC group. We concluded that that the contents and the tyrosine phosphorylation of IRS-2 protein had obvious time trait after exercise.

关 键 词：动力学 酪氨酸 骨骼 肌肉 

分 类 号：O313[理学—一般力学与力学基础] Q517[理学—力学]