儿童肺炎支原体感染与IgE水平的相关性研究  

Research of serum IgE in mycoplasma pneumoniae infected children

作　　者：张蔓莉[1] 孙跃红[1] 江毅[1] 龙泽民[1] 冯国富[1] 周雅燕[2] 苗春巍 

机构地区：[1]广东省深圳市蛇口人民医院儿科,518066 [2]深圳市儿童医院呼吸科 [3]吉林省白城市洮北区妇幼保健院

出　　处：《中国妇幼保健》2008年第36期5148-5150,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨肺炎支原体感染与血清IgE的相关性。方法:采用放射免疫法对89例肺炎支原体感染患儿在治疗前及治疗后恢复期进行血清IgE水平测定,并对非肺炎支原体感染不伴有喘息的呼吸道感染患儿58例及正常对照组儿童50例检测血中IgE水平。结果:肺炎支原体感染患儿血清IgE水平较正常对照组儿童和普通呼吸道感染患儿IgE水平均有显著升高(P<0.01),肺炎支原体感染患儿治疗前及治疗后恢复期其血清IgE水平比较有显著性差异(P<0.01),肺炎支原体感染患儿恢复期血清IgE水平与正常对照组儿童及非支原体感染患儿血清IgE水平比较差异无显著性意义。结论:肺炎支原体感染时血清IgE水平升高,且与肺炎支原体感染引起的慢性咳嗽存在一定关系。Objective： To discuss the relevance of mycoplasma pneumoniae infection and serum IgE. Methods： Serum IgM level was detected in 89 mycoplasma pneumoniae patients before trentment and after recovery and respiratory infection patients, 58 of non - myco- plasma pneumoniae infection non- pneumonia mycoplasma with asthma and 50 controls by radioimmunoassay （RIA） . Results： The serum IgE of mycoplasma pneumoniae patients was significantly elevated than that of controls （P 〈 0.01 ） and that of non mycoplasma pneumoniae infection （P 〈 0.01 ） and before trentment compared to that after re-covery. There was no significant difference between mycoplasma pneumoniae patients before trentment and controls （ P 〉 0. 05 ） and non mycoplasma pneumoniae infection and controls （ P 〉 0. 05） . Conclusion： Serum IgM is elevated and correlative to chronic cough during mycoplasma pneumoniae infection.

关 键 词：肺炎支原体 血清IGE 儿童 

分 类 号：R725.6[医药卫生—儿科]