蚁王风湿灵胶囊镇痛、抗炎作用的实验研究  

Experimental study on the analgesic and anti-inflammatory effect of the Yiwangfengshiling capsule

作　　者：吕菁菁[1] 房志仲[1] 李晓华[1] 杨金荣[1] 

机构地区：[1]天津医科大学药学院药剂学教研室,天津300070

出　　处：《天津医科大学学报》2008年第4期452-455,共4页Journal of Tianjin Medical University

摘　　要：目的:研究蚁王风湿灵胶囊的镇痛、抗炎作用。方法:采用药理实验方法对本品的镇痛、抗炎作用进行观察。镇痛实验采用热板法和醋酸扭体法;抗炎实验采用小鼠耳廓肿胀模型、大鼠足肿胀模型、大鼠棉球肉芽肿模型,以及对小鼠和大鼠皮肤毛细血管通透性影响的观察。结果:蚁王风湿灵胶囊与空白对照组对照存在显著性差异。结论:蚁王风湿灵胶囊有明显的镇痛、抗炎作用。Objective： To study the analgesic and anti-inflammatory effect of the Yiwangfengshiling capsule. Methods： The analgesia effect of Yiwangfengshiling capsule was observed by hot-plate procedure and torsion body method.The anti-inflammatory effects were observed on the pinna swelling model mice, the voix pedis swelling model rats, the cotton ball granuloma model rats. The permeation capability of capillary vessel on the curls was determined. Results： The effect of Yiwangfengshiling capsule had obvious difference contrasted to the blank group. Conclusion： Yiwangfe ng capsule has obvious analgesic and anti-inflammatory effects.

关 键 词：蚁王风湿灵胶囊 镇痛 抗炎 动物实验 

分 类 号：R965[医药卫生—药理学]