特比萘芬治疗儿童头癣59例疗效和安全性评价  

Efficacy and Security Evaluation of Terbinafine for Tinea Capitis in 59 Children

作　　者：路永红[1] 周培媚[1] 苏晓杰[1] 向丹黎[1] 扶平[1] 吴红兵[1] 吴童迅[1] 

机构地区：[1]成都市第二人民医院皮肤科,四川成都610017

出　　处：《中国皮肤性病学杂志》2008年第12期768-768,I0001,共2页The Chinese Journal of Dermatovenereology

基　　金：成都市医学重点学科基金资助(成卫科教[2007]44号)

摘　　要：目的探讨特比萘芬治疗儿童头癣的疗效及安全性。方法将59例患儿随机分为两组,治疗组口服特比萘芬,同时采用剃发、洗头、搽药、用具消毒、日晒等方法治疗;对照组仅口服特比萘芬。两组的疗程均为12周。结果治疗组临床治愈率为79.31%,真菌学治愈率为72.41%,完全治愈率为68.97%;对照组依次为50.00%,46.67%和36.67%。未达真菌学治愈的真菌菌种以犬小孢子菌居多,共19(32.20%)例。结论剃发、洗头、擦药、用具消毒、日晒同时口服特比萘芬可明显提高头癣的完全治愈率。Objective To study the efficacy and security of terbinafine combined with complementary therapy for tinea capitis in children. Methods Divide 59 children patients into treatment group and control group in the treatment group children orally take terbinafine combined tonsuring washing head daubing drugs sterilized appliance and sun - shining;In control group patients only orally take terbinafine, both groups treatment lasted for 12 weeks. Results The clinical cure rate of treated group was 79.31%, the mycological cure rate was 72.41% and the rate of complete cure was 68.97%. The clinical cure rate of control group was 50.00%, the mycological cure rate was 46.67% and the rate of complete cure was 36.67%. There were no obvious adverse reaction and function lesion of liver and kidney, the type of most of the fungi that not reached mycological cure were microsporum canis. （ 19 examples,32.20% ）. Conclusion Orally taken terbinafine combined tonsuring, washing head, daubing drugs, boiling appliance and sun - shining can heighten the rate of complete cure obviously,it can be a choice for the clinical.

关 键 词：儿童 头癣 特比萘芬 治疗 

分 类 号：R756.1[医药卫生—皮肤病学与性病学]