正交法优选温胆颗粒的挥发油提取工艺  

Optimization of Extraction Conditions of Volatile Oil in Wendan Granules by Orthogonall Menthod

作　　者：潘林梅[1] 朱华旭[1] 曾明飞[1] 

机构地区：[1]南京中医药大学中医药研究院,南京江苏210029

出　　处：《现代中药研究与实践》2008年第6期70-71,共2页Research and Practice on Chinese Medicines

基　　金：江苏省教育厅高新技术产业推进项目(JHB06-33)

摘　　要：目的探讨温胆颗粒中挥发油提取的最佳工艺。方法以水蒸气蒸馏法提取处方中的挥发油,以挥发油得率作为评价指标,应用L934正交设计,考察浸泡时间、加水量、提取时间三个因素的影响。结果最佳提取工艺为加水10倍量,浸泡0.5h,提取8.0h结论所确定的工艺对挥发油提取稳定、操作简便,易于工业化生产控制。Objective To optimize the extraction condition of volatile oil in Wendan granules. Methods Taking the extracted amount of volatile oil as the index, the orthogonal experiment was applied to optimize. Results The best extraction conditions were established as 10-fold water, macerate 0.5h and distillation for 8h. Conclusion The extraction process is feasible and stable, and applicable to industrial production.

关 键 词：温胆颗粒 挥发油 工艺优选 

分 类 号：R944.27[医药卫生—药剂学]