北京城乡结合部与市区人群亚临床颈动脉硬化研究  

Subclinical carotid atherosclerosis in urban or suburban populations in Beijing

作　　者：师绿江[1] 武留信[1] 李更茹[1] 宋蕾[1] 黄靖[1] 姜媛媛[1] 

机构地区：[1]解放军空军航空医学研究所,北京100142

出　　处：《中华健康管理学杂志》2008年第6期338-342,共5页Chinese Journal of Health Management

基　　金：国家“十五”科技攻关资助项目（2001BA703B01）

摘　　要：目的研究北京城乡结合部与市区自然人群亚临床颈动脉硬化特征，为实施心血管疾病风险监测与健康管理提供依据。方法参照ARIC方案，从2002年10月至2007年9月对北京市2101例自然人群（分为市区组899例和城乡组1202例两组）进行高分辨率B超颈动脉检查，测量双侧颈总动脉近端、远端和窦部的内中膜厚度（IMT）、颈总动脉斑块，颈总动脉内径并计算动脉紧张度，比较两种不同区域人群上述指标分布特征。结果两组人群颈总动脉IMT随着年龄增长而增加（男性均P〈0．05，女性均P〈0．05），男女各年龄段城乡结合部人群IMT明显厚于市区人群（均P〈0．05）。无论男女，两组人群颈动脉斑块检出率随着年龄增长而增加（男性均P〈0．05，女性均P〈0．05），城乡结合部人群斑块检出率明显高于市区人群（均P〈0．05）。两组人群颈动脉紧张度随年龄增加呈现减低趋势（均P〈0．05），城乡结合部人群减低趋势更加明显（P〈0．05）。结论随着我国城市化和老龄化进程加快，心血管疾病风险监测与健康管理的重点人群应放在城乡结合部人群和中老年人群。Objective To describe the characteristics of subclinical carotid atherosclerosis in urban or suburban populations to provide support for cardiovascular risk factors monitoring and health management. Methods A population-based cardiovascular epidemiology survey was conducted among 899 urban and 1202 suburban residents in Beijing from October 2002 to September 2007. Carotid plaque, intimamedia thickness （IMT） , and lumen diameter were measured in the proximal, distal, and sinus segment of the carotid artery using duplex ultrasound. Arterial tension and the number of plaques were calculated and compared between the two groups. Results Mean common carotid IMT increased with age in both groups （P 〈 0. 05 ,respectively）, and among all age groups IMT was obviously thicker in suburban population than that in urban population （ respectively, P 〈 0. 05 ） . Independence of gender, the prevalence of plaques increased with age （ P 〈 0. 05 ） , and the number of plaques was higher in the suburban population than those in urban population in all age groups （P 〈 0. 05 ）. However, arterial tension decreased with age in both groups, especially in the suburban populations （P〈 0. 05 ）. Conclusion With the acceleration of urbanization and aging in China, cardiovascular risk factor monitoring and health management should focus on suburban and elderly populations.

关 键 词：颈动脉 超声检查 健康管理 

分 类 号：R54[医药卫生—心血管疾病]