URIT-12快速血红蛋白分析仪与CoulterLH-750的对比研究  

Comparison between Coulter LH-750 and URIT-12 for measuring hemoglobin concentration

作　　者：秦雪[1] 刘燕萍[2] 林发全[1] 易珍[1] 徐明辉[3] 李若林[3] 李泰阶[3] 李山[1] 

机构地区：[1]广西医科大学第一附属医院临床医学实验部,广西南宁530021 [2]广西医科大学 [3]广西医科大学研究生学院,广西南宁530021

出　　处：《南方医科大学学报》2008年第12期2196-2198,共3页Journal of Southern Medical University

基　　金：广西卫生厅科研课题(z2008158)

摘　　要：目的探讨URIT-12血红蛋白分析仪快速测定血红蛋白的可行性研究。方法应用CoulterLH-750全自动血细胞仪和URIT-12血红蛋白分析仪分别测定100份本院住院患者血样本的血红蛋白浓度。结果URIT-12快速血红蛋白分析仪与CoulterLH．750全自动血细胞分析仪测定结果相比，差异无统计学意义（P〉0．05），两者结果高度相关（r=0.994）；URIT-12测定结果的线性范围为（46-240）g／L；取低、中、高3份样本重复测定20次，URIT-12批内变异CV值分别为2．13％、2．17％、2．33％，均小于3％；取高脂肪血清、高黄疸血清、高球蛋白血清、高白细胞血做干扰实验，结果前三者对两仪器测定干扰率均小于4％，而高白细胞血对URIT-12测定结果的干扰率为10％，LH-750为7％。结论URIT-12血红蛋白分析仪测定结果准确性好、精密度高，是一种操作简单、检测快速的便携式血红蛋白测定仪。Objective To evaluate the feasibility of URIT-12 hemoglobin analyzer for fast measurement of hemoglobin concentration. Methods Hemoglobin concentration was detected in 100 random blood samples using URIT-12 hemoglobin analyzer and Coulter LH-750 hematology analyzer. Results The two analyzers sfiowed good correlation of the results （r=0.994） without significant difference between them （P〉0.05）. The linear range of URIT-12 hemoglobin analyzer was 46-240 g/L, and in the repeated measurements （20 times） of 3 batches of blood samples with low, moderate and high hemoglobin concentrations, the within-batch coefficient of variation of URIT-12 hemoglobin analyzer, from low to high concentrations, were 2.13%, 2.17%, and 2.33%, respectively. In the measurement of 4 batches of high-fat, high-bilirubin, high-globin and high-white-blood-cell blood samples, the interference rate of the former 3 samples were all less than 4% by the two devices, but that of the fourth sample was 10% by URIT-12 hemoglobin analyzer and 7% by Coulter LH-750 analyzer. Conclusion The results detected by URIT-12 hemoglobin analyzer have high accuracy and precision and is easy to operate, fast-testing and portable.

关 键 词：血红蛋白测定 氰化高铁血红蛋白法 叠氮高铁血红蛋白法 

分 类 号：R446.1[医药卫生—诊断学]