新生儿先天性甲状腺功能减退症筛查中TSH切值的探讨  

Exploration of cut-off value of TSH during screening of congenital hypothyroidism in the newborns

作　　者：陈肖肖[1] 秦玉峰[1] 曲一平[1] 毛华庆[1] 施玉华[1] 赵正言[1] 

机构地区：[1]浙江大学医学院附属儿童医院,杭州310003

出　　处：《中华内分泌代谢杂志》2008年第6期639-640,共2页Chinese Journal of Endocrinology and Metabolism

基　　金：基金项目：浙江省科技厅科研基金重点项目（G20020584）

摘　　要：新生儿筛查中发现，TSH水平与先天性甲状腺功能减退症（CH）检出率呈直线正相关。当TSH切值点分别为9、10、15和20mU／L时，CH阳性检测敏感度分别为99．77％、96．80％、81．25％和71．88％。TSH〉9mU／L是较好的切点。Positive linear correlation was found between TSH level and detection rate of congenital hypothyroidism （CH）. When measured with a cut-off point at 9, 10, 15 and 20 mU/L of TSH, the sensitivity of positive detection rate for CH was 99.77%, 96.80%, 81.25% and 71.88%, respectively. TSH 〉 9 mU/L seems to be a reasonable cut-off value.

关 键 词：新生儿筛查 甲状腺功能减退症 促甲状腺素 参考值 

分 类 号：R722.1[医药卫生—儿科]