微波消解-电感耦合等离子体质谱法测定怀牛膝中重金属元素含量  

Determination on Heavy Metals Content of Achyranthes bidentata Blume through Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

作　　者：李宇伟[1] 王新民[1,2] 连瑞丽[1] 魏志华[1] 介晓磊[1] 陈士林[2] 

机构地区：[1]郑州牧业工程高等专科学校,河南郑州450011 [2]中国医学科学院中国协和医科大学药用植物研究所,北京100094

出　　处：《安徽农业科学》2008年第33期14582-14584,共3页Journal of Anhui Agricultural Sciences

基　　金：中国第41批博士后科学基金面上项目(20070410616);河南省杰出青年科学基金项目(074100510018)

摘　　要：[目的]建立微波消解-电感耦合等离子体质谱（ICP-MS）的方法，测定怀牛膝中铅、镉、汞、砷含量。[方法]优化ICP-MS的操作条件，将样品进行微波消解，以^114In作为内标，补偿基体效应，采用ICP-MS法同时测定上述4种元素。[结果]对于所测元素，标准曲线的相关系数r〉0．9995，回收率为96．7％～106．4％，RSD〈11．2％；样品测定结果表明，供试怀牛膝药材重金属超标现象较为严重、[结论]该研究建立的微波消解-ICP-MS法简便、快速、准确、灵敏度高，可为不同产地不同种类的中药材提供重金属含量的测定方法，用于中药材的质量控制、[ Objective] The inductively coupled plasma mass spectrometry （ICP-MS） was constructed to determine the contents of Lead, Cadmium, Mercury and Arsenic in Arch）romhes bidentata Blume [ Method] Through the optimum operation of ICP-MS, the samples were digested by microwave. The element ^114 In was taken as an internal standard element to compensate body effect and ICP-MS method was used to detemaine the contents of Lead,Cadmium,Mercury and Arsenic. [Result] For the delermined elements, the correlation coefficient （r） of standard curve was over 0.999 5 and recovery tale was from 96.7 % to 106.4% while RSD was less than 11.2%. The result of determination showed that the heavy metal content in Arch3,ranthes bidentata Bhune beyond standard was serious. [ Conclusion ] The constructed ICP-MS method with sinrple operation, rapid response, aecuracy and high sensitMty in this experi- ment could be used for quality control of Chinese Medicinal Materials by detecting heavy metal contents in different Chinese Medicinal Materials from origi nal places.

关 键 词：微波消解 电感耦合等离子体质谱(ICP-MS) 怀牛膝 重金属 

分 类 号：S567.239[农业科学—中草药栽培]