心脏X综合征双嘧达莫负荷心肌^201 Tl SPECT显像分析  被引量:8

Dipyridamole ^201Tl myocardial SPECT imaging in patients with syndrome X

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作  者:蒋锦琪[1] 陈良[1] 谢文晖[2] 张鹏[1] 林启蓉[1] 

机构地区:[1]上海市胸科医院急诊科,200030 [2]上海市胸科医院核医学科,200030

出  处:《中华核医学杂志》2008年第6期375-377,共3页Chinese Journal of Nuclear Medicine

摘  要:目的观察心脏X综合征患者的双嘧达莫负荷心肌^201 Tl SPECT显像特点,分析其表现机制。方法选取临床符合心脏X综合征诊断标准的患者29例,按体质量0.56mg/kg予双嘧达莫,于4min内静脉注射,10及240min后分别进行双嘧达莫负荷心肌^201 Tl SPECT显像,原始图像经三维重建后由2位以上有经验的核医学科医师进行分析。结果所有29例患者的双嘧达莫负荷“Tl图像(10min)均显示左室心肌放射性分布正常。延迟(240min)显像时有25例(86.2%)患者(共200个节段)出现部分心肌节段反向放射性分布稀疏或缺损,即“反向再分布”,共累及34个节段:前壁6个(17.6%)、下壁10个(29.4%)、前间壁4个(11.8%)、心尖部11个(32.4%)、前侧壁3个(8.8%),后间壁、后侧壁和后壁无放射性分布异常;其余4例(13.8%)患者延迟显像则为放射性分布正常。结论双嘧达莫负荷心肌”Tl SPECT显像的“反向再分布”现象对于心脏X综合征的诊断具有一定的临床意义。Objective The aim of the study was to clarify the imaging characteristics of dipyridamole 201 Tl SPECT myocardial imaging in patients with syndrome X. Methods Twenty-nine patients diagnosed with syndrome X were enrolled in this study. They all underwent dipyridamole (intravenous injection of 0.56 mg/kg within 4 min) ^201Tl SPECT myocardial perfusion imaging. Images were interpreted by more than two experienced nuclear medicine physicians. Results In stress images showed normal in all. In resting images, 86.2% (25/29) were abnormal with perfusion defects at anterior wall in 6 (17.6%) , at inferior wall in 10 (29.4%), at antero-septal wall in 4 ( 11.8% ), at apex in 11 (32.4%), and at antero-lateral wall in 3 (8.8%). Conclusion High correlation of reverse redistribution of dipyridamole 201Tl SPECT myocardial imaging and syndrome X was observed.

关 键 词:微血管性心绞痛 体层摄影术 发射型计算机 单光子 双嘧达莫 铊放射性同位素 

分 类 号:R686[医药卫生—骨科学]

 

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