干预治疗对肥胖儿童颈动脉弹性指标的影响  

Effect of Intervention Treatment on Carotid Artery Elasticity in Obesity Children

作　　者：高启旺[1] 兰颖[1] 温德惠[2] 王义成[2] 

机构地区：[1]北京市昌平区中医院超声科,北京102200 [2]河北北方学院附属第一医院超声科,河北石家庄050000

出　　处：《医学临床研究》2008年第12期2178-2180,共3页Journal of Clinical Research

摘　　要：【目的】探讨对肥胖儿童实施干预治疗后颈动脉弹性功能的变化。【方法】利用血管回声跟踪(Echo-Tracking,ET)技术检测肥胖儿童干预治疗前、后双侧颈动脉弹性系数(Eρ)、硬化度(β)、顺应性(AC)及内中膜厚度(IMT),比较干预治疗前及治疗6个月、1年后各指标的变化。【结果】与干预治疗前比较:治疗后6个月Eρ、β降低,有统计学差异(P<0.05),AC增高,但差异无统计学意义(P>0.05);治疗后1年Eρ、β降低,AC增高,均有统计学差异(P<0.05)。治疗1年与治疗6个月的组间比较:Eρ、β降低,AC增高,均有统计学差异(P<0.05)。治疗前后IMT变化均无统计学意义(P>0.05)。【结论】ET技术可早期、敏感、无创的评价肥胖儿童干预治疗效果,并可动态随访。[Objective]To explore the effect of intervention on carotid artery elasticity in obesity children. [Methods] An ultrasonic echo-tracking technology was used to measure obesity children＇s elastic modulus （Eρ）, the stiffness constant （β）, arterial compliance （AC） and intima-media thickness （IMT） of the common carotid arteries in obesity children. These indices were compared before and after intervention. [Results]Eρand β after intervention were lower than those before intervention, and the difference was significant （ P 0.05）. AC after intervention was higher than that before intervention, but the difference was not statistically significant （ P 〉0.05）. One year later, Eρand β decreased and AC increased, and there was significant difference （ P 〈0.05）. Eρand β after intervention for one year were lower and AC higher than those after intervention for six months, and there was significant difference （ P 〈0.05, P 〈0.05）. The changes of IMT before and after intervention had no statistical significance. [Conclusion] ET technology is an early, sensitive, noninvasive method to detect the effect of intervention treatment on carotid artery elasticity in obesity children.

关 键 词：肥胖症/治疗 颈动脉 

分 类 号：R589.204[医药卫生—内分泌]