无创性估测左室心肌松弛时间常数的新方法  

A New Method for Noninvasive Estimating of the Time Constant of Left Ventricular Relaxation

作　　者：范觉新[1,2] 张运[1,2] 张梅[1,2] 赵玉霞[1,2] 张薇[1,2] 钟敬泉[1,2] 隋树建[1,2] 

机构地区：[1]山东省烟台市烟台山医院 [2]山东医科大学附属医院心内科

出　　处：《中国超声医学杂志》1998年第2期52-54,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：为了进一步探讨无创性定量评价左室心肌松弛时间常数（τ）的可靠方法，本文在２８例舒张性心力衰竭（ＤＨＦ）患者中，进行了心导管和多普勒超声心动图同步性研究，并提出了利用无创技术估测τ的新方法。笔者利用多普勒超声心动图和颈动脉搏动图等无创技术估测左室等容舒张期始点、末点压力和等容舒张时间三项参数，在与心导管资料测值获得较好相关基础上，分别将无创估测的三个参数代入下列三参数指数方程ＩｎＰｅ＝Ａ·ＩＶＲＴ＋ＩｎＰｏ，据此式导出左室心肌松弛时间常数（τｎ），并将τｎ与心导管测量的τｔ值进行了对比研究，结果显示两者之间高度相关（Ｐ＜０．００１，ｒ＝０．７１）。为此，建立了无创性定量评价左室心肌松弛时间常数的新方法。To explore a new reliable method for noninvasive estimating the time constant of left ventricular(LV)relaxation(τ),Doppler echocardiography and dual catheters were performed in 28 patients with diastolic heart failure(DHF),and a new noninvasive method for estimating τ (τ n)was suggested in the paper.The 3 exponential parameters of LV pressure decay(the beginning and ending pressures of LV pressure decay,and the isovolumetric relaxation time,IVRT),were measureed by Doppler echocardiography and carotid cardiogram.On the basis of a higher correlation with the data of the catheterization,the 3 exponential parameter equation(InPe=A·IVRT+InPo)was rewritten by the 3 parameters measured noninvasively,and the time constant of LV relaxation(τ n)was noninvasively calculated in accordance with the equation.The result showed a higher r value(r=0 71,p<0 001)between τ n and τ t measured by catheter.The method in this paper provides a new way in the noninvasive evaluation of the time constant of LV relaxation and offers comprehensive estimation of LV diastolic performance.

关 键 词：左室 心肌松驰时间 常数 心导管检查 超声心动图 

分 类 号：R540.45[医药卫生—心血管疾病]