质谱法测定鲑鱼降钙素及其类似物  

Determination of Salmon Calcitonin and Its Analogs by Mass Spectrometry

作　　者：蔡耘[1] 杨彬[1] 邱丰和[1] 王杰[1] 杨松成[1] 

机构地区：[1]军事医学科学院国家生物医学分析中心

出　　处：《分析测试学报》1998年第1期76-78,共3页Journal of Instrumental Analysis

摘　　要：应用快原子轰击质谱（ＦＡＢ＿ＭＳ）、电喷雾质谱（ＥＳＩ＿ＭＳ）及基质辅助激光解吸附飞行时间质谱（ＭＡＬＤＩ＿ＴＯＦ＿ＭＳ）分别测定了鲑鱼降钙素类似物，得到了准确的分子质量信息，并对这３种方法的准确度及灵敏度进行了比较。Salmon calcitonin and its analogs were determined by FAB_MS,ESI_MS,and MALDI_TOF_MS and accurate molecular mass informations were obtained.The sensitivity and accuracy of the three methods are compared.All of their RSD are less than 0 2 %.

关 键 词：鲑鱼 降钙素 FAB ESI WALDI TOF MS 

分 类 号：R977.1[医药卫生—药品]