急性脑卒中患者血糖水平与死亡及残疾关系  

Relationship between admission blood glucose and clinical outcome in acute stroke patients during hospitalization

作　　者：王宁[1] 鞠忠[1,2] 张欢[1] 张艳芬[3] 许锬[1] 张永红[1] 

机构地区：[1]苏州大学医学部放射医学与公共卫生学院流行病学教研究室,苏州215123 [2]内蒙古通辽市科尔沁区医院 [3]内蒙古通辽市医院

出　　处：《中国公共卫生》2009年第1期30-31,共2页Chinese Journal of Public Health

摘　　要：目的探讨急性脑卒中患者入院血糖水平与住院期间发生死亡、残疾的关系。方法收集内蒙古通辽市6家医院2003年1月～2005年12月的3938例脑卒中患者基线资料，进行血糖检测；采用Logistic回归模型进行统计分析。结果调整了年龄、性别、民族、吸烟史、饮酒史及血压后，入院血糖≥7．0mmol／L组的脑卒中患者住院期间发生死亡的OR为8．227（95％CI=4．122～16．420），发生复合结局（死亡或残疾）的OR为2．043（95％CI=1．494～2．793）。趋势检验分析结果显示，脑卒中患者住院期间发生死亡和复合结局（死亡或残疾）的危险性有随着入院血糖水平升高而增高的趋势。结论入院高血糖可能是脑卒中患者住院期间死亡及复合结局的独立危险因素，应在急性期积极控制血糖水平。Objective To investigate the relationship between admission blood glucose level and in-hospital death and disability in acute stroke patients. Methods 3 938 acute stroke patients in six hospitals in Tongliao city, Inner Mongolia from January,2003 to December,2005 were investigated for admission blood glucose and other baseline materials. Multiple Logistic model was used to analyze the relations between blood glucose level and the risk of in-hospital death and disability in acute stroke patients. Results ORs of in-hospital death and combined outcome（ death or disability） associated with blood glucoses〉7.0 mmol/L were 8. 227 （ 95% CI = 4. 122 - 16. 420 ） and 2. 043 （ 95% CI = 1. 494 - 2. 793 ）, respectively. After adjustment for age, gender, ethnic, cigarette smoking, alcohol drinking and blood pressure,there was a tendency of increased risk of in-hospital death and combined outcome（ death or disability） with elevated blood glucose at hospital admission. Conclnsion Hyperglycemia at hospital admission may be an independent risk factor of in-hospital death and combined outcom in acute stroke patients. The present study suggested that blood glucose should be controlled actively post-stroke.

关 键 词：血糖 脑卒中 死亡 残疾 

分 类 号：R543[医药卫生—心血管疾病]