速度向量成像与定量组织速度成像技术评价犬急性心肌缺血状态下左心室收缩功能  

Evaluation of left ventricular systolic function of acute myocardial ischemia with velocity vector imaging and quantitative tissue velocity imaging in dogs

作　　者：张川[1] 查道刚[1] 白园园[1] 吴小苑[1] 杜荣生[1] 刘伊丽[1] 

机构地区：[1]南方医科大学南方医院心血管内科,广州市510515

出　　处：《临床超声医学杂志》2008年第12期796-799,共4页Journal of Clinical Ultrasound in Medicine

基　　金：国家自然科学基金(30870721)

摘　　要：目的以心导管测量左室压力上升速度最大值(+dp/dtmax)为标准,探讨应用速度向量成像(VVI)与定量组织速度成像(QTVI)评价犬急性心肌缺血状态左室收缩功能。方法健康杂种犬6只,开胸后游离左冠状动脉回旋支或前降支,使用自制动脉血管缩窄器制备不同程度冠状动脉狭窄。测量不同血流状况下二尖瓣环水平4个心室壁处(左室间隔、下壁、侧壁、前壁)心肌收缩速度,同时进行心导管检查,测量+dp/dtmax。结果使用VVI技术测量,二尖瓣环水平心肌收缩速度与左室+dp/dtmax呈正相关(r=0.883),P<0.001;使用QTVI技术测量,二尖瓣环处心肌收缩速度与+dp/dtmax呈正相关(r=0.715),P<0.001,两相关系数行Z检验,Z=2.981,P=0.0028。结论VVI或QTVI技术测定二尖瓣环水平心肌收缩速度均是评价左心室收缩功能的好方法。相对于QTVI而言,VVI与+dp/dtmax的相关性更高,可能更加适用于对左室收缩功能的测定。Objective To explore the value of velocity vector imaging （WI） or quantitative tissue velocity imaging （QTVI） in evaluating left ventricular systolic function of acute myocardial ischemia in dogs. Methods Six healthy mongrel dogs were enrolled in this study. After opening of the chest, left circumflex artery or left anterior descending artery was encircled, with a flow probe and a home - made artery constrictor was placed around the proximal coronary to produce different grades of coronary artery stenosis. Peak systolic velocity of four ventricular walls （left veutricular septum, inferior wall, lateral wall, anterior wall） around the Initral annulus were recorded with VVI or QTVI in different status of coronary blood flow. Left ventricular ＋ dp/dt max was measured by cardiac catheter at the same time. Results There was good linear correlation between longitudinal systolic velocity of myocardium around the mitral valve and ＋ dp/dt max with VVI （ r = 0. 883, P 〈 0. 001 ）. There was significant correlation between longitudinal systolic velocity and ＋ dp/dt max with QTVI （ r = 0. 715, P 〈 0. 001 ）. The coefficient correlation was Z = 2. 981, P = 0. 0028. Conclusion Both WI and QTVI are good methods to evaluate left ventricular systolic function. VVI has closer linear correlation with ＋ dp/dt max than QTVI. There is significant difference between the two methods.

关 键 词：心室功能 左 速度向量成像 定量组织速度成像 犬 

分 类 号：R541.4[医药卫生—心血管疾病] R542.22[医药卫生—内科学]