Rh阴性血型筛查及其抗体检测的临床意义  

Clinical Significance of RhD-negative Screening and the Detection of its Antibody

作　　者：董伟群[1] 何洁[2] 詹淑芬[3] 

机构地区：[1]昆明医学院第一附属医院输血科 [2]成都军区昆明总医院干细胞与组织器官工程研究中心 [3]昆明医学院第一附属医院检验科,云南昆明650032

出　　处：《昆明医学院学报》2008年第6期105-107,共3页Journal of Kunming Medical College

摘　　要：目的对Rh阴性血型的筛查及其抗体的检测,为临床预防溶血性输血反应和新生儿溶血病的发生提供实验室依据.方法用抗D(IgM)血型定型试剂对13 208例受检者进行Rh血型鉴定.通过盐水法、聚凝胺法、间接抗人球蛋白法检测Rh阴性血中的抗体.结果13 208例受检者中,检出Rh(D)阴性75例,其中检出Rh血型免疫性抗体5例.结论常规对Rh阴性血型进行筛查及其抗体的检测,对预防溶血性输血反应,新生儿溶血病的发生及安全输血有着重要的临床意义.Object ve To provide laboratory proof for the precaution of hemolytic transfusion reaction and hemolytic disease of newborn by RhD -negative screening and the detection of its antibody. Methods The Rh（D） blood types were detected by anti-IgD（IgM） blood grouping reagents, and the antibodies were detected by Saline method, Polybrene test and Indirect antiglobulin test. Results 75 samples Rh（D）-negative were detected in 13 208 samples, including 5 samples Rh（D） blood type immunity antibody. Conclusion It is very important for Rh（D）-negative screening and the detection of its antibody to prevent hemolytic transfusion reaction and hemolytic disease of newborn and blood transfusion in safety by conventional approach.

关 键 词：RH(D)阴性 抗体 溶血性输血反应 新生儿溶血病 

分 类 号：R457[医药卫生—治疗学]