甲磺酸罗哌卡因与盐酸罗哌卡因用于腋路臂丛神经阻滞的对比研究  

Comparative study of Ropivacaine Mesylate and Ropivacaine Hydrochloride for axillary brachial plexus block

作　　者：王伟华[1] 张青[1] 侯喜龙[1] 

机构地区：[1]辽宁省大连市第二人民医院麻醉科,辽宁大连116011

出　　处：《中国医药导报》2009年第1期67-68,共2页China Medical Herald

摘　　要：目的:比较甲磺酸罗哌卡因与盐酸罗哌卡因用于腋路臂丛神经阻滞的有效性和安全性。方法:48例ASAⅠ～Ⅱ级择期上肢手术患者随机分为0.5%盐酸罗哌卡因组(A组)和0.596%甲磺酸罗哌卡因组(B组)。每组24例,两组患者均行腋路臂丛神经阻滞,观察感觉与运动神经阻滞起效时间、持续时间及不良反应,评价麻醉效果。结果:在感觉与运动神经阻滞的起效时间、持续时间及不良反应方面,0.596%甲磺酸罗哌卡因与0.5%盐酸罗哌卡因未见明显差异。结论:0.596%甲磺酸罗哌卡因与0.5%盐酸罗哌卡因应用于腋路臂丛神经阻滞,具有相似的有效性和安全性。Objective： To compare the efficacy and safety of Ropivacaine Mesylate and Ropivacaine Hydrochloride for axillary brachial plexus block. Methods： 48 ASA Ⅰ or Ⅱ patients scheduled for upper extremity surgery were randomly divided into two groups： 0.5% Ropivacaine Hydrochloride group （group A） and 0.596% Ropivacainc Mesylate group （group B）, with 24 patients in each group. All patients were performed with axillary brachial plexus block. Then the initiating time, lasting time of sensory and motor block as well as the adverse reaction were observed, and the anesthetic effect was evaluated. Results： No significant difference of the initiating or lasting time, or even the adverse reaction of sensory and motor block was observed between the two groups. Conclusion： 0.5% Ropivacaine Hydrochloride and 0.596% Ropivaeainc Mesytate have similar efficacy and safety in the application of axillary brachial plexus block.

关 键 词：甲磺酸罗哌卡因 盐酸罗哌卡因 腋路臂丛神经阻滞 

分 类 号：R971.2[医药卫生—药品]