瘀创灵凝胶的制备及质量控制  

Preparation and Quality Control of Yuchangling Gels

作　　者：刘丹[1] 刘超英[1] 韩建伟[1] 

机构地区：[1]湖北中医学院中药资源与中药复方省部共建教育部重点实验室,武汉430061

出　　处：《中国药师》2009年第1期26-28,共3页China Pharmacist

基　　金：湖北省教育厅资助项目(D20081608)

摘　　要：目的:制备瘀创灵凝胶并制定质量控制的方法。方法:以卡波姆为基质制备瘀创灵凝胶,用薄层色谱法对方中的当归、血竭进行鉴别,HPLC法测定延胡索乙素的含量。结果:薄层色谱中检出当归、血竭,延胡索乙素在0.11～1.15μg内线性关系良好,平均回收率101.36%,RSD为2.01%。结论:该处方设计合理,制备方法可行,质量控制方法可靠。To prepare the Yuchuangling gels and establish a quality control method. Method： Yuehangling Gels was prepared with carbomer as base. Radix angelica sinensis and sanguis draeonis were identified by TLC. The content of tetrahydropalmatine was determined by HPLC. Result： The spots in TLC were clear and distinguished well. The calibration curve of tetrahydropalmatine was linear between 0.11 - 1.15 μg. The recovery was 101.36% with RSD 2.01%. Conclusion ： The formula is rational. The preparation and quality control is reliable.

关 键 词：瘀创灵凝胶 薄层色谱 高效液相色谱 质量控制 

分 类 号：R283.69[医药卫生—中药学]