扶正消瘤液增强LAK抗肿瘤活性的实验研究  

作　　者：许运明 吴明生[1,2] 王自安 徐立春[1,2] 

机构地区：[1]江苏省扬州市中医院 [2]江苏扬州大学医学院肿瘤免疫治疗中心

出　　处：《辽宁中医杂志》1998年第4期188-189,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：江苏省科委及扬州市卫生局资助

摘　　要：以黄芪、紫草、土茯苓、灵芝等组成的中药复方“扶正消瘤液”在体外与白细胞介素Ⅱ（ｒＩＬ－２）共同诱导ＬＡＫ细胞，将ｒＩＬ－２浓度降低为常规浓度的１０％，ＬＡＫ刺激指数仍可达１８．５３，与不用扶正消瘤液比较，有显著性差异（Ｐ＜０．０５）。并且，其对胃癌细胞株ＳＧＧ７９０１的杀伤率，较常规浓度ｒＩＬ－２诱导的ＬＡＫ细胞无显著差异（Ｐ＞０．０５）。提示扶正消瘤液可促进ＬＡＫ增殖。Fuzhengxiaoliu Decoction(FD) which consists of Huangqi,Zicao,Tufulin,Linzhi,etc.together with rIL-2,induced LAK cell out of body.It decreased the concentration of rIL-2 to 10% of normal.SI of LAK still kept 18.53 and had significant difference,contrasted with non-FD(P<0.05),Moreover its rate of killing SGG7901 had no significant difference,contrasted with LAK cell induced by rIL-2 of normal concentration.It indicates FD promote the reprocluction of LAK and enforce the activity of LAK against tumour.

关 键 词：扶正消瘤液 LAK细胞 白细胞介素2 实验 

分 类 号：R286.91[医药卫生—中药学] R285.5[医药卫生—中医学]