血液显微图像中红细胞计数系统的研究与实现  

Erythrocyte Counting System Based on Blood Micrograph

作　　者：蒋洁[1,2] 樊德宁[3] 陈旺[3] 熊志辉[3] 

机构地区：[1]怀化医学高等专科学校,组织与胚胎教研室湖南怀化418000 [2]中南大学湘雅医学院,组织与胚胎教研室,湖南长沙410073 [3]国防科学技术大学信息系统与管理学院系统工程系,湖南长沙410073

出　　处：《医学信息》2009年第1期8-10,共3页Journal of Medical Information

摘　　要：血细胞计数在现代临床检验工作中发挥着非常重要的作用。本文基于数字图像处理技术,研究血液显微图像的红细胞计数方法,通过分析红细胞的先验知识,得到显微图像中红细胞在直方图中的特征。并在此基础上,对图像进行二值化、孔洞填充、腐蚀、膨胀等一系列处理以去除噪声,最后在考虑细胞粘连、重叠的情况下对细胞数量进行基于面积的统计。设计了原型系统并用实验验证和分析了其有效性。Erythrodyte counting is an important task in modem clinic inspection. In this paper, an approach of erythrocyte counting for blood micrograph based on digital image processing technique is proposed. Firstly the feature of erythrocyte in histogram of blood micrograph can be get via analyzing the prior knowledge of erythrocyte, then a series of operations-binaryzation, hole-filling, eroding, dilating are been carried on to the micrograph to denoise it, and lastly the counting problem based on region area statistic even under the situations of erythrocyte conglutination and overlapping is studied. A corresponding prototype system is designed and implemented and its validity is tested via experiments.

关 键 词：血液显微图像 红细胞计数 腐蚀 膨胀 直方图 

分 类 号：R446.113[医药卫生—诊断学] R445[医药卫生—临床医学]