右旋布洛芬缓释胶囊的初步稳定性试验  

The Stability Test of Modified Release Capsule of Dex-ibuprofen

作　　者：杨成雄[1] 张勇慧[2] 

机构地区：[1]荆楚理工学院化工与药学院,湖北荆门448000 [2]华中科技大学同济药学院,湖北武汉430030

出　　处：《荆门职业技术学院学报》2008年第12期59-63,共5页Journal of Jingmen Technical College

摘　　要：目的:考察右旋布洛芬缓释胶囊的初步稳定性考察。方法:通过光照试验、加速试验和长期试验,对右旋布洛芬缓释胶囊的外观性状、色泽、溶出度、含量和有关物质等指标进行考察,并预测其有效期。结果:在各受试条件下各样品外观无显著变化,含量和溶出度无明显差异,有关物质量稍有增加。结论:本品较稳定,各时间检测样品与0时比较无明显差异,可以对制定右旋布洛芬缓释胶囊的有效期提供参考。Objective：The stability test of modified release capsule of Dex - ibuprofen. Methods： The stability test of modified release capsule of Dex - ibuprofen had been done by illumination test ,accelerated test and long test run ; inspected its character,colour, dissolution and relate material, and calculated its expiration date. Results： Its character,eolour, dissolution and eonteat had not been changed exclude relate material, but all in amplitude. Conclusion： The stability test of modified release capsule of Dex - ibuprofen was good and offerred a reference to its expiration date.

关 键 词：右旋布洛芬 缓释胶囊 稳定性考察 

分 类 号：R927.11[医药卫生—药学]