硅灰石/磷灰石-锰锌铁氧体磁性生物活性玻璃的性能评价  

Properties of apatite-wollastonite magnetic glass-ceramics doped by Mn-Zn ferrite

作　　者：毛茂[1] 林云[2] 周大利[1] 李光大[1] 郭筵[1] 陈国生[2] 潘涛华[2] 

机构地区：[1]四川大学材料科学与工程学院,四川省成都市610064 [2]四川大学华西口腔医学院,四川省成都市610041

出　　处：《中国组织工程研究与临床康复》2008年第45期8863-8866,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：采用经煅烧合成的锰锌铁氧体粉与硅灰石/磷灰石生物活性玻璃陶瓷前驱体粉复合煅烧,制备了锰锌铁氧体磁性生物活性玻璃,观察了锰锌铁氧体中锰和锌的比例对磁性生物活性玻璃晶相组成、力学性能、磁学性能以及生物活性的影响。结果表明虽锰和锌的比例不同,但是样品的主晶相均为硅灰石、磷灰石、氟磷灰石和分子式为Mn0.75Zn0.75Fe1.5O4的锰锌铁氧体。掺入铁氧体提高了材料的力学性能,材料的抗弯强度随着锌含量的增加而呈现先上升后下降的趋势;不同比例的锰和锌影响了复合材料的磁性,并且锌的含量在一定的时候材料饱和磁化强度较大。在模拟体液中浸泡14d后各样品表面都长出了球状的羟基磷灰石颗粒沉淀,掺杂不同锰锌比例的锰锌铁氧体对材料的生物活性未造成显著影响。Novel magnetic bioactive glass-ceramics （MGC） were synthesized by doping calcined Mn-Zn ferrite with different ratio of Mn and Zn in apatite-wollastonite glass-ceramics （A-WGC）. The phase composition, mechanical performance, magnetic performance and bioactivity of MGC were studied. The results show that the main phases of MGC are wollastonite, apatite, flourapatite and Mn-Zn ferrite of Mn0.75Zn0.75Fe1.5O4. The mechanical performance is increased by doping ferrite in A-WGC. The materials show better bending strength and saturation magnetization with a certain ratio of Mn and Zn. After 14 days a hydroxyapatite layer formed on the surface of all the samples. Doping ferrite does not show distinct influence on the bioactivity of MGC.

关 键 词：锰锌铁氧体 磁性生物活性玻璃陶瓷 抗弯强度 磁滞损耗 生物活性 

分 类 号：R318[医药卫生—生物医学工程]