各种植骨材料治疗骨缺损的优缺点比较(英文)  

Various materials in bone grafting therapy for bone defects

作　　者：徐军[1] 许超蕊[2] 刘佰弘[3] 田军[1] 

机构地区：[1]哈尔滨医科大学附属第二临床医院骨科,黑龙江省哈尔滨市150086 [2]黑龙江省医院老年病科,黑龙江省哈尔滨市150036 [3]山东省文登整骨医院创伤科,山东省文登市264000

出　　处：《中国组织工程研究与临床康复》2008年第45期8997-9000,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：骨移植是治疗骨缺损的主要方法,同时也是骨科最常用的治疗方法之一。传统的移植材料是自体骨,具有骨生成能力强、容易愈合的特点,但因来源有限、二次伤害、增加感染机会等原因限制其临床应用;同种异体骨不具有自身成骨能力,愈合主要靠骨传导作用和骨诱导作用,移植骨的抗原性是影响同种异体骨与宿主愈合的重要因素;异种骨主要障碍是免疫排斥反应;人工骨成骨方式单一,修复不彻底,愈合过程缓慢,缺乏生物活性。Bone grafting is not only the main treatment for bone defects, but also one of the most common treatment methods for orthopedic. Autogenous bone is traditional material of bone grafting, which has strong bone formation ability and the characteristics of easy healing, but it is limited in source, increases chances of infection, such as restrictions on the reasons for its clinical application. Allogeneic bone osteoblasts do not have their own ability to heal, which mainly rely on the role of bone induction and bone conduction. Bone transplantation antigenicity is an impact factor of allogeneic bone healing with the host; Immunological rejection is the main obstacle to bone xenograft. Artificial bone is unsatisfactory due to a single way of bone formation, not completely restored, slow healing process and lack of biological activity.

关 键 词：骨移植 移植 骨缺损 综述文献 

分 类 号：R318[医药卫生—生物医学工程]