BinaxNOW疟疾快速诊断试剂卡现场应用效果  

Field evaluation of BinaxNOW~ rapid diagnostic devices for malaria

作　　者：刘慧[1] 贾瑞海 李春富[1] 聂仁华[1] 孙院红[1] 李贵深 沈旭 

机构地区：[1]云南省寄生虫病防治所,普洱665000 [2]英维利斯医疗器械北京有限公司 [3]缅甸掸邦第二特区勐冒县医院 [4]云南省普洱市人民医院

出　　处：《中国血吸虫病防治杂志》2008年第6期449-451,共3页Chinese Journal of Schistosomiasis Control

摘　　要：目的评价BinaxNOW疟疾快速诊断试剂卡现场应用效果。方法采用BinaxNOW疟疾快速诊断试剂卡检测临床"四热"病人,以镜检法为金标准,计算敏感性和特异性等指标。实验采用双盲法。结果使用BinaxNOW疟疾快速诊断试剂卡检测"四热"病人443例,检出疟疾阳性151例。总体敏感性为98.69%,特异性为100%,与镜检符合率为99.55%;检测恶性疟原虫的敏感性和特异性分别为100%和99.66%,与镜检符合率为99.76%;检测非恶性疟的其他疟原虫的敏感性和特异性分别为90.91%和100%,与镜检符合率为99.36%。结论BinaxNOW疟疾快速诊断试剂卡质量稳定、可靠,特异性、敏感性高。Objective To evaluate the effect of BinaxNOW rapid diagnostic devices for malaria in the field. Methods The symptomatic patients were detected by using the BinaxNOW devices and the results were compared with the microscopic examination of Giemsa-stained blood smears （as a golden standard）. The sensitivity and specificity were calculated. The double-blind method was used in this study. Results In 443 symptomatic patients, 151 cases were positive for malaria. The sensitivity was 98. 69% and the specificity was 100%, and the coincidence rate of BinaxNOW with the microscopic examination was 99.55%. The sensitivity and specificity of Plasmodium falciparum were 100% and 99.66%, respectively, and the coincidence rate was 99.76%. The sensitivity and specificity of non-falciparum Plasmodium were 90. 91% and 100%, respectively, and the coincidence rate was 99.36%. Conclusion The BinaxNOW rapid diagnostic devices for malaria are sensitive, specific,and stable for malaria diagnosis in the field.

关 键 词：BinaxNOW疟疾快速诊断卡 疟疾 疟原虫 免疫诊断 效果评价 

分 类 号：R531.3[医药卫生—内科学]