180例冠心病危险因素与冠状动脉病变特点分析  

A Study on Risk Factors and Coronary Artery Lesions Characteristics in 180 Cases of Coronary Heart Disease

作　　者：卢卓强[1] 晋学庆[1] 

机构地区：[1]福建医科大学附属第一医院心内科,福州350001

出　　处：《中国医药导刊》2008年第9期1346-1348,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨福建地区冠心病(CHD)的危险因素与CHD患者冠状动脉病变特点。方法:根据冠状动脉造影结果将258例患者分为CHD组(n=180)和对照组(n=78),分析CHD患者的危险因素和冠状动脉病变特点。结果:冠状动脉病变者180例,CHD组各种危险因素在发生频率前3位是:高龄(73.33%)、低高密度脂蛋白胆固醇(HDL-C)(67.78%)、高血压(61.67%):累积病变血管共375支,好发血管依次为左前降支、右冠状动脉、左回旋支、左主干;血管狭窄程度以75%～99%为主197支(52.53%);患者多以三支病变为主71例(39.44%);CHD组的性别、高龄、合并吸烟、高血压、高纤维蛋白原(FG)和高密度脂蛋白胆固醇/总胆固醇(HDL-C/TC)、LDL-C异常及FG、HDL-C/TC、LDL-C值与对照组存在显著差异(P<0.05),2组间糖尿病发病率、HDL-C、TC、TG(甘油三酯)无显著差异(P>0.05)。结论:高纤维蛋白原(FG)可能为CHD的危险因素,CHD患者中合并糖尿病的比例并不高,福建地区CHD的危险因素为:男性、高龄、吸烟、高血压、高FG、低HDL-C/TC、高LDL-C,冠脉的病变支数与严重程度随危险因素的个数增多而增加。Objective： To approach the risk factors and coronary artery tesions characteristics of coronary heart disease （CHD） in patients of Fujian. Methods：258 cases were divided into 2 groups according the coronary aagiography （CAG） Results： CHD group （n=180） and control group （n=78）. Analysis the risk factors and coronary artery lesions characteristics of CHD. Results：180 patients had coronary ＇artery lesions. The top three frequency of risk factors happened in CHD group were Advanced age（73.33%）,Low serum level of HDL-C（67.78%）, Hypertension （61.67%）. 375 branches were danmged, among which, 149 branches were LAD. 116 were RCA. 97 were LCX. 13 were LM. Most of tire stenosis were between 75% to 99%, amount to 197 brmlches （52.53%）. Most of the CHD groups were tri-branehes injury 71 cases （39.44%） There were significant differences between two groups on sex,advanced age,smoking, hyperterusion, FG, HDL-C/TC,LDL-C and the levels of FG, HDL-C/TC, LDL-C（P〈0.05）. There were no significant difference on diabetes, HDL-C, TC,TG（P〉0.05）. Conclusion： High serum level of FG is also a possible risk factor of CHD, the incidence of diabetes in CHD group is low, The risk factors of CHD in Fujian are：male, advanced age,smoking, hypertension, high serum levels of FG and LDL-C, low ratio of HDL-C/TC. The more risk factors were. tbe more serious the coronary artery stenosis and more number of damaged branches.

关 键 词：冠心病 冠状动脉造影 危险因素 病变特点 

分 类 号：R541.4[医药卫生—心血管疾病]