广东省输入性丝虫病病例调查  

Follow-up Survey on the Imported Cases of Lymphatic Filariasis in Guangdong Province

作　　者：张贤昌[1] 黄少玉[1] 邓卓晖[1] 欧作炎[1] 伍卫平[2] 骆雄才[1] 陈锡欣[3] 张启明[1] 林荣幸[1] 阮彩文[1] 王金龙[1] 崔惠儿[1] 

机构地区：[1]广东省疾病预防控制中心,广州510300 [2]中国疾病预防控制中心寄生虫病预防控制所,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,上海200025 [3]山东省寄生虫病防治研究所,济宁272133

出　　处：《中国寄生虫学与寄生虫病杂志》2008年第6期409-411,共3页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：目的调查广东省输入性丝虫病病例及对周围人群的影响。方法对广东省输入性丝虫病病例及周围人群进行检查,应用常规厚血膜双片法检查微丝蚴,ELISA法检测丝虫IgG4抗体。结果2007年9月在广州南沙、番禺、汕头和中山等4市(区)共调查989人,其中47人来自广西富川县朝东镇长塘行政村的干上和印山自然村。共发现3例微丝蚴血症者,均为疫点长塘村干上、印山自然村人,微丝蚴密度分别为24、20和2条/120μl血,微丝蚴检出率为6.4%(3/47)。对残存疫点在粤人员、周围人群及非流行区对照人群共1501人进行丝虫IgG4检测,丝虫IgG4阳性者15例,其中来自干上和印山村12例,阳性率为25.5%(12/47),高于其他人群(χ2=295.83,P<0.01)。IgG4阳性而非微丝蚴血症者采用快速免疫色谱测试卡(ICT)复查,结果均为阴性。结论广东省来自广西丝虫病疫点务工人群中存在少量传染源。Objective To make a survey on the possible imported cases with microfilaremia from a recently identified outbreak focus in Fuchuan County of Guangxi Region. Methods Moving people as temporary laborers from Guangxi and periphery residents were screened by thick blood smears for mierofilariae and ELISA for specific IgC,4 in Sept 2007. Results 989 persons in cities/districts of Nansha, Panyu, Shantou and Zhongshan were investigated. Among 150 persons from Changtang administrative village of Guangxi, 47 were from two outbreak focuses, Ganshang and Yinshan natural villages in Changtang. Three cases with microfilaremia were found, with a mierofilariemia density of 24, 20 and 2 per 120 0,1 blood, respectively. The 3 cases were all from the 2 natural villages, with a microfilariemia positive rate of 6.4% （3/47）. Meanwhile, anti-filaria IgG4 was detected for other 1 501 persons, including those from the outbreak focuses, from surr-ounding areas and from non-endemic area as control, fifteen cases were found with IgG4 positive. Of the 15 positive cases, 12 were from the 2 outbreak natural villages, with a positive rate of 25.5%, higher than those of others （χ^2=295.83, P〈0.01）. The cases with IgG4 positive but mierofilaremia negative were reexamined by ICT kit and all showed negative. Conclusion It is suggested that no further transmission occurs although microfilaremia cases have beeen imported from the outbreak focus of Guangxi.

关 键 词：丝虫病 疫点 微丝蚴血症者 传播 

分 类 号：R532.15[医药卫生—内科学]