MCV,MCH,RDW,HBDH联合检测在贫血诊治中的临床应用  

Clinical Application of Combination Check of MCV, MCH, RDW and HBDH in Anaemia Diagnosis and Treatment

作　　者：丁蔚[1] 张立新[1] 叶军[1] 金梅[1] 陆桃红[1] 

机构地区：[1]江苏省泰州市人民医院检验科,江苏泰州225300

出　　处：《深圳职业技术学院学报》2008年第4期36-39,共4页Journal of Shenzhen Polytechnic

摘　　要：探讨平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)、红细胞分布宽度(RDW)、α-羟丁酸脱氢酶(α-HBDH)联合检测在贫血诊断和疗效观察中的价值。对贫血患者的外周血标本检测MCV,MCH,RDW,α-HBDH,并进行分析。结果显示:①缺铁性贫血(IDA)、巨幼红细胞性贫血(MA)、骨髓增生异常综合症(MDS)患者的MCV与正常对照组比较差异有显著性,温抗体(型)自身免疫性溶血性贫血(WAIHA),MA,AA,MDS组的MCV比IDA组高,MA组的MCV还比AA组的高,(P<0.05);②M A、IDA组与正常对照组的MCH比较时差异有显著性,MA,AA,WAIHA,MDS组的MCH比IDA组高,MA组的MCH还比AA、WAIHA组的高,(P<0.05);③ID A,MA,WAIHA,MDS患者的RDW-CV与正常对照的差异有显著性,(均P<0.05);④M A,WAIHA,MDS患者的α-HBDH与正常对照比较时差异有显著性,MA,WAIHA组的α-HBDH水平比IDA、AA组高,(P<0.05);⑤MC V、α-HBDH在治疗前后的差异有显著性,两组MCV与α-HBDH均有相关性。四项参数的联合检测有助于常见贫血的鉴别诊断及疗效观察。To examine clinical value of combination check of MCV, MCH, RDW and HBDH in anaemia diagnosis and treatment, MCV, MCH, RDW and HBDH in the peripheral blood specimen of patients suffering from anaemia were tested. The results show that： 1. there was significant difference in MCV between patients with IDA, MA, MDS group and the normal controls group. MCV of WAIHA, MA, AA, MDS group was higher than that of IDA group, MCV of MA group was higher than that of AA group, （p〈0.05）; 2. There was significant difference in MCH between patients with MA, IDA group and the normal controls group. MCV of MA, AA, WAIHA group was higher than that of IDA group, MCH of MA group was higher than that of AA, WAIHA group, （p〈0.05）; 3. There was significant difference in RDW-CV between patients with IDA, MA, WAIHA, and MDS group and the normal controls group （p〈0.05）; 4. There was significant difference in α-HBDH lever between patients with MA, WAIHA and MDS group and the normal controls group, α-HBDH lever of MA and WAIHA group was higher than that of IDA and AA group, （p〈0.05）; 5. There was significant difference in MCV and α-HBDH lever between patients with prior treatment and that of post-treatment. There is correlation between MCV and α-HBDH lever in either group with prior or post-treatment （p〉0.05）. Combination check of the four parameters is of great help for anemia diagnosis and curative effect observation.

关 键 词：平均红细胞体积 平均红细胞血红蛋白含量 红细胞分布宽度 Α-羟丁酸脱氢酶 贫血 

分 类 号：R556[医药卫生—血液循环系统疾病]