富勒烯衍生物对自由基的清除作用及其生物学效应  

The ability of fullerene derivatives to eliminate free radicals and their biological effects

作　　者：孙权[1] 蔡建明[1] 黄越承[1] 

机构地区：[1]第二军医大学放射医学研究室,上海200433

出　　处：《国际放射医学核医学杂志》2008年第5期308-311,共4页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：基金项目：国家自然科学基金（30770503）;全军医药卫生“十一五”攻关项目（06G60）

摘　　要：富勒烯及其衍生物因其独特的化学结构和理化性质，尤其是它们强大的清除自由基的能力，引起了生物医学界研究者的极大关注，开展了大量生物学效应研究，近年来取得较大进展。在此重点探讨多种富勒烯衍生物的生物学效应，特别是对自由基清除效应的应用意义及应用前景。The unique chemical and physical properties of buckminsterfullerene （C^o） and its derivatives, especially the excellent ability to eliminate free radicals, have generated increasing interest for researchers in the field of biomedicine. Subsequently, considerable investigations have been conducted into the biological effects of C60, and remarkable progress has been made in recent years. In this paper, we mainly review the biological effects of various C60 derivatives, particularly on the free radical scavenging effect and its significance in practical application.

关 键 词：富勒烯 自由基 抗氧化效应 

分 类 号：O[理学]