我院普外科急性化脓性阑尾炎抗菌药物应用分析  

Analysis of Application of Antibacterial Drugs in Department of General Surgery

作　　者：孙艳[1] 谢牧牧[1] 

机构地区：[1]中国人民解放军总医院药品保障中心第一临床药局,北京100853

出　　处：《中国药业》2009年第1期45-46,共2页China Pharmaceuticals

摘　　要：目的分析中国人民解放军总医院制定《抗菌药物临床规范使用实施细则》前后,普外科治疗急性化脓性阑尾炎应用抗菌药物时执行细则的规范情况。方法回顾性调查2005年11月至2007年10月急性化脓性阑尾炎患者抗菌药物的应用情况并进行统计分析。结果规范抗菌药物使用后,患者平均住院日由6.76d缩短为5.48d;抗菌药物使用率较高的品种为甲硝唑、头孢呋辛、依替米星,基本符合一线用药要求,平均使用天数由4.53d缩短为3.95d;术前用药率由34.38%增加到48.39%,用药时机适当;抗菌药物联用率有所降低。结论规范用药后,抗菌药物的应用基本符合规范,应该在医院各临床科室进一步推广。Objective To analyze the application of antibacterial drugs in single disease such as curing acute suppurative appendicitis in the department of general surgery before and after Detailed Rules of Standard Application of Antibacterial Drugs in Clinic was applied in our hospital. Methods To review the antibacterial drugs used for the appendectomy patients during November, 2005 to October, 2007, and to group the data into pre- standardized and post- standardized. Results After the antibacterial drugs were standardized, the average hospitalization was shortened from 6.76 d to 5.48 d; the high- used antibacterial drugs were metronidazole, cefuroxime, etilmicin, which measured up the criterion on the whole, the average periods antibacterial drugs used were cut from 4.53 d to 3.95 d; the administration before operation raised from 34.38% to 48.39% and the occasion was appropriate; the drugs combination was reduced. Conclusion After the antibacterial drugs were standardized, the application was basically accorded with the criterion, and the criterion should be spread to the whole hospital because of its good effect.

关 键 词：抗菌药物 急性化脓性阑尾炎 规范 分析 

分 类 号：R969.3[医药卫生—药理学] R978[医药卫生—药学]