自发性膝关节骨坏死的病因及发病机制  

Etiology and Pathogenesis of Spontaneous Osteonecrosis of the Knee

作　　者：陈广刚[1] 郭万首[1] 

机构地区：[1]中日友好医院骨科

出　　处：《医学综述》2009年第1期5-7,共3页Medical Recapitulate

摘　　要：自发性膝关节骨坏死多发生于60岁以上的老年女性，典型的临床表现是膝关节突发的疼痛与压痛，病灶常为单侧．多数累计股骨内髁及胫骨内侧平台软骨下骨，晚期往往需要行膝关节置换术。该病的确切发病原因及发病机制目前仍不清楚，主要有应力引起的微骨折和血管缺血两种理论，现将近年来该病病因及发病机制的报道进行简要综述。Spontaneous ostenecrosis of the knee （SONK） was typically a disease of the elderly over 60 years old ,predominantly female patients, characterized by severe knee pain of sudden onset, unilateral involvement, and restriction of the lesions generally to one femoral condyle or tibial plateau, with predilection for the medial compartment of the joint. In endstage,knee arthroplasty should be conducted for its therapy. The exact etiology and precise pathogenesis remain unclear. Both micro-fracture caused by stress and vascular insufficiency have been discussed, although neither has been confirmed. This article reviewed the papers related to its etiology and pathogenesis in recent years.

关 键 词：膝关节自发性骨坏死 病因 发病机制 

分 类 号：R681.8[医药卫生—骨科学]