清肺口服液拮抗呼吸道合胞病毒感染的血清药理学研究  

Study on Qingfei Oral Liquid Antagonizing RSV Infection with Serum Pharmacology Methods

作　　者：赵长江[1] 袁斌[2] 徐建亚[1] 王莉[1] 孔飞[1] 

机构地区：[1]南京中医药大学,江苏南京210029 [2]江苏省中医院,江苏南京210029

出　　处：《中国中医药信息杂志》2009年第1期34-35,共2页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：江苏省自然科学基金(BK2005219)

摘　　要：目的评价清肺口服液抗呼吸道合胞病毒(RSV)的活性。方法采用MTT法,以利巴韦林为对照组,观察清肺口服液及不同给药方式对RSV的拮抗作用。结果清肺口服液具有明显抗RSV的作用,与利巴韦林比较差异无统计学意义;清肺口服液的作用机制可能为抑制病毒吸附或增殖。结论清肺口服液可以通过不同环节拮抗RSV病毒,是治疗RSV感染的有效复方制剂。Objective To evaluate the anti-RSV activity of Qingfei Oral Liquid. Method With Ribavirin as the control, the antagonistic effect of Qingfei Oral Liquid and different administration methods on RSV infection were observed by MTT technology. Result Qingfei Oral Liquid had obvious effection of anti-RSV, showing no significant difference compared with Ribavirin. The action mechanism may be that Qingfei Oral Liquid has inhibition effects on adsorption or proliferating of RSV. Conclusion Qingfei Oral Liquid can antagonize RSV through different linkages. It is an effective compound preparation for treating RSV infection.

关 键 词：清肺口服液 呼吸道合胞病毒 中药血清药理学 

分 类 号：R285.5[医药卫生—中药学]