蒙药甘露益肝滴丸提取工艺研究  

Technology research of Mongolian Medicine Mannan nourshing liver pills

作　　者：包桂花[1] 巴根那[1] 白明纲[1] 哈斯[1] 康廷国[2] 

机构地区：[1]内蒙古民族大学,通辽028000 [2]辽宁中医药大学,沈阳110032

出　　处：《中国民族医药杂志》2008年第11期58-59,63,共3页Journal of Medicine and Pharmacy of Chinese Minorities

摘　　要：目的:为蒙药甘露益肝滴丸优化乙醇渗漉提取工艺条件。方法:采用L9(34)正交表设计试验,HPLC法测定评价指标胡椒碱的提取转移率,同时考察总浸出物,结果进行方差分析。结果:最佳工艺条件为A1B2C1方案,主要影响因素依次为乙醇浓度(A,P<0.01)、渗漉速度(C,P<0.01)、乙醇用量(B,P<0.05)。结论:制备蒙药甘露益肝滴丸,乙醇渗漉提取荜茇等药材的最佳工艺参数为,取药物粗粉,要用8倍量(B2)的90%乙醇(A1)、以1ml/min的速度(C1)依法缓缓渗漉。胡椒碱的转移率可达99%。Objective： To Mongolian medicine Ganluyigan dropping pills Optimization percolation method the extraction process. Method： L9 （3^4） orthogonal design of experiments, HPLG method of evaluation index piperine transfer rate of extraction, leaching of the total inspection at the same time, the results of analysis of variance. Results： The best of conditions is A1B2C1 programme, main factors were alcohol concentration （A, P 〈 0.01 ）, percolation Speed （ C, P 〈 0.01 ）, alcohol consumption （ B, P 〈 0.05）. Conclusion： Prepares Ganluyigan dropping pills, alcohol percolatio method extraction Bibo and other ingredients from the best technical parameters for, to use eight times the amount （B2） of 90% alcohol （A1）, Must be 1ml/min speed （C1） in accordance with the law slowly percolation, piperine the transfer rate of up to 99 %.

关 键 词：甘露益肝滴丸 胡椒碱 渗漉法 提取工艺 正交设计 

分 类 号：R291.2[医药卫生—民族医学]