心内膜MAP与血清心肌酶的测定在诊断缺血所致室性心律失常时的应用  

APPLICATION OF ENDOCARDIUM MAP AND SERUM MYOCARDIUM ENZYME ASSAY IN DIAGNOSIS OF VENTRICULAR ARRHYTHMIA CAUSED BY ISCHEMIA

作　　者：肖业伟[1] 何光凤[2] 杭永伦[3] 刘希秀[1] 冯志强[1] 盘强文[1] 

机构地区：[1]泸州医学院生理教研室,四川泸州646000 [2]泸州医学院附属医院医教科,四川泸州646000 [3]泸州医学院附属医院药剂科,四川泸州646000

出　　处：《泸州医学院学报》2008年第6期620-622,共3页Journal of Luzhou Medical College

基　　金：四川省教育厅青年基金项目(2005B014)

摘　　要：目的:观察心内膜MAP与血清心肌酶在心律失常中的变化,探讨其临床意义。方法:15只家兔,在心肌缺血背景下致心律失常前后分别记录、检测各项观察指标,作前后对照比较。结果:造模后cTnI、Mb、CK-MB高于造模前(P<0.05),造模前MAP各指标与造模后有显著差异(P<0.05)。结论:心律失常时心内膜MAP的特征性形态变化结合血清心肌酶指标是判断早期心肌缺血、心律失常的一种快速、可靠的方法。Objective： To observe the changes of endocardium MAP and serum myocardium enzyme in arrhythmia and discuss its clinical significance. Methods：In 10 rabbits, the changes of each items were recorded under the myocardium ischemia background before and after the occurence of arrythmia and compared. Results： cTnI, Myo, CK-MB were higher after the arrythmia model was made（P〈0.05）, the various MAP indexes were significantly different before and after the model was formed （P〈0.05）. Conclusion： The changes of endocardium MAP combined with the blood serum myocardium enzyme assay to diagnose earlier myocardial ischemia and arrythmia is a reliable and fast method.

关 键 词：室性心律失常 MAP 肌钙蛋白I 肌红蛋白 肌酸激酶同工酶 

分 类 号：R331.3[医药卫生—人体生理学] R541.7[医药卫生—基础医学]