珍珠明目眼用即型凝胶的质量标准研究  

Study on quality standard of Zhenzhu Mingmu In Situ Forming System for Ocular Drug Delivery

作　　者：代龙[1] 

机构地区：[1]山东中医药大学,山东济南250355

出　　处：《齐鲁药事》2008年第12期726-729,共4页qilu pharmaceutical affairs

摘　　要：目的制定珍珠明目眼用即型凝胶的质量标准。方法用薄层色谱法鉴别了冰片以及珍珠水解液中的丙氨酸、甘氨酸；用气相色谱法测定了冰片的含量。结果薄层色谱阳性结果明显，冰片在0．1988-1．9885μg范围内呈线性关系，加样回收率为100．46％。结论方法稳定可靠，可作为该即型凝胶的质量控制方法。OBJECTIVE To study the quality standard of Zhenzhu Mingmu In Situ Forming System for Ocular Drug Delivery. METHODS Borneol,alanine and glycine were identified by TLC,borneol was determined by GC. RESULTS The results of TLC is dearly, borneol showed a good linear relationship at a range of 0. 1988 - 1. 9885μg, the average recovery was 100.46%. CONCLUSION The method was accurate and can be used for the quality control of Zhenzhu Mingmu In Situ Forming System for Ocular Drug Delivery.

关 键 词：珍珠明目滴眼液 即型凝胶 冰片 质量标准 气相色谱法 

分 类 号：R927.11[医药卫生—药学]