超敏C反应蛋白与绝经后女性冠心病发病的相关性研究  

Study of the relationship between hs-CRP and CHD in post-menopausal women

作　　者：刘浩[1] 石礼[1] 王同成[1] 

机构地区：[1]济南市第三人民医院心内科,山东省250101

出　　处：《中国心血管病研究》2008年第10期748-749,共2页Chinese Journal of Cardiovascular Research

摘　　要：目的探讨超敏C反应蛋白(hs-CRP)预测绝经后女性冠心病的价值。方法选择100例绝经后女性患者,分为冠心病组55例,非冠心病组为45例。对比两组患者的超敏C-反应蛋白、血脂及血清雌二醇有无差异,采用SAS统计软件进行处理分析。结果①绝经后女性冠心病组的血清hs-CRP水平明显高于非冠心病组[(5.28±3.95)mg/L比(1.78±1.28)mg/L,P<0.05]。②冠心病组的血清雌二醇水平低于非冠心病组[(80.46±12.39)pmol/L比(113.62±16.87)pmol/L,P<0.05]。③绝经后女性冠心病血清hs-CRP水平与血脂及雌二醇之间无相关性。结论血清hs-CRP与绝经后女性冠心病的发病有明显的关系,血清hs-CRP水平升高可作为预测绝经后女性冠心病发生的危险因素。Objective To investigate the value of hs-CRP to predict CHD in post-menopause female. Methods 100 cases were divided into CHD group（55 cases）and non CHD group（45 cases）. To investigate the difference of hs-CRP,blood lipid and E2 level in blood serum between post-menopause female CHD patients and non CHD patients. Results （1）There is obvious difference of CRP levels betwene CHD group and non-CHD group [ （5.28±3.95）mg/L vs （1.78±128）mg/L,P〈0.05 ]. （2）There is obvious difference of E2 levels betwene CHD group and non-CHD group[ （80.46±12.39）pmol/L vs （113.62±16.87）pmol/L,P〈O.05]. （3）There is no relationship betwene hs-CRP and E2 in post-menopause female. Conclusion There is close relationship between the levels of CRP and CHD on post menopausal patients. Hs-CRP is a useful factor to predict CHD in post menopausal women.

关 键 词：超敏C-反应蛋白 绝经后 冠心病 血清雌二醇 

分 类 号：R541.4[医药卫生—心血管疾病]