生物活性玻璃复合自体骨髓移植治疗青少年单纯性骨囊肿  

Simple bone cysts in teenagers treated by grafting of bioactive glass and autologous bone marrow

作　　者：刘宏伟[1] 孙俊英[1] 宋兵华[1] 杨兴[1] 王勇[1] 朱二山[1] 

机构地区：[1]苏州大学附属第一医院骨科,苏州市十梓街188号215006

出　　处：《中国矫形外科杂志》2009年第1期11-13,共3页Orthopedic Journal of China

摘　　要：[目的]探讨生物活性玻璃复合自体骨髓移植治疗青少年单纯性骨囊肿的疗效。[方法]2005年4月～2007年10月手术治疗青少年单纯性骨囊肿16例,其中男10例,女6例;平均年龄18.5岁(12～30岁)。肱骨近端8例,股骨近端5例,胫骨上端2例,桡骨远端1例。囊壁彻底搔刮处理后,将适量的生物活性玻璃(bioactive glass,BG)复合取得的自体骨髓紧密填塞入骨缺损空腔,5例合并移位的病理性骨折予钢板或髓内钉固定。[结果]治疗后6个月内X线片显示所有囊腔骨化,平均愈合时间18周,随访6～32个月,平均18个月,未见明显并发症发生,无病例复发。[结论]生物活性玻璃复合自体骨髓移植治疗青少年单纯性骨囊肿创伤小、安全、操作简单,疗效满意。[ Objective] To investigate the therapeutic results of grafting with bioactive glass and autologous bone marrow for simple bone cyst in teenagers. [ Method] From April 2005 to October 2007, 16 teenagers with simple bone cyst were reported. There were ten males and six females with a mean age of 18. 5 years （range 12 to 30 years） . Eight cysts were in the proximal humerus, five in the proximal femur, two in the proximal tibial and one in the distal end of radius. Lining of cavity was removed thoroughly with a curet. The cyst cavity was filled with the mixtures of 45s bioactive glass and autogenous red bone marrow. Five cases of pathologic fracture were fixed with steel plate or intramedullary nail. [ Result] All 16 cases of cysts were ossifted radiolo gically within six months, with an average time to syst healing of 18 week. A follow- up of 6 to 32 months （mean 18 months） showed satisfactory healing without complications. [ Conclusion] The combined grafting with bioactive glass and autologous bone marrow appears to be an effective and simple treatment for simple bone cyst in teenagers.

关 键 词：生物活性玻璃 骨囊肿 骨髓 自体 

分 类 号：R687.3[医药卫生—骨科学]