一少数民族乡发热史人员两次疟疾间接荧光抗体实验结果比较  

Comparison of malaria indirect immunofluorescent antibody test in people with fever history from an ethnic minority township

作　　者：刘慧[1] 魏春[1] 许建卫[1] 黄国珍[1] 许时燕[1] 

机构地区：[1]云南省寄生虫病防治所,云南普洱665000

出　　处：《中国病原生物学杂志》2008年第12期927-928,939,共3页Journal of Pathogen Biology

基　　金：WHO/ADB加强少数民族中的疟疾防治试点研究(No.WPMVP/2005/ICP/MAL/1.2/001)

摘　　要：目的通过比较两次发热史人员疟疾间接荧光抗体实验(IFAT)结果,评价一个少数民族边境乡的疟疾发病和流行程度的变化。方法分别于2006年8月和2007年8月,2次采集前一年有发热史人员的血清样品,进行疟疾荧光抗体检测。结果2006年8月和2007年8月采集的血样IFAT阳性率分别为71.6%(95%CI66.6%～76.2%)和45.9%(95%CI38.2%～69.5%),差异有统计学意义(P<0.01)。两次检测IFAT滴度≥1∶80者分别占21.89%和15.92%。结论该乡疟疾发病和流行程度较上一年度显著下降;发热史人员的IFAT可用于弥补当地发热病人血检技术之不足。Objective To evaluate the change of malaria incidence and prevalence in a border township of ethnical minorities through comparing the results of two rounds of indirect immunofluorescent antibody test （IFAT） of people with fever history. Methods Serological samples were respectively collected in August 2006 and 2007 from people with fever episodes within one year before the investigations, and then IFAT were carried out in laboratory. Results The IFAT positivity rates of serum samples collected in August 2006 and 2007 were respectively 71.6% （95%CI 66.6%-76.2%） and 45.9%（95%CI 38.2%-69.5%）, which were significantly different（P〈0.01）. The titer ≥1∶80 proportion of two IFAT rounds were respectively 21.89% and 15.92%. Conclusion Compared to the former year, malaria incidence and prevalence are significantly declined （P〈0.01）. IFAT targeted people with fever history can make up disadvantages of local microscopy skill in fever patient examination.

关 键 词：疟疾 间接荧光抗体试验 发热史 

分 类 号：R531.3[医药卫生—内科学]