罗非鱼性别决定和分化机制的研究进展  

Research advances on sex determination and differentiation mechanism in tilapia

作　　者：邹芝英[1] 杨弘[1] 李大宇[1] 

机构地区：[1]中国水产科学研究院淡水渔业研究中心农业部水生动物遗传育种和养殖生物学重点开放实验室,江苏无锡214081

出　　处：《中国水产科学》2009年第1期139-145,共7页Journal of Fishery Sciences of China

基　　金："国家重点基础研究发展计划973计划"项目(2004CB117401);国家科技支撑计划专题(2006BAD01A1202);2007年公益性行业(农业)科研专项(nyhyzx07-044)

摘　　要：罗非鱼染色体遗传型性别决定机制(Chromosomal genetic sex determination,GSD)的研究开展较早,目前利用种间杂交的方法得到全雄罗非鱼在生产上已广泛应用,而对影响罗非鱼性别决定的环境因素研究开展较晚。研究证实罗非鱼确实存在温度依赖型性别决定机制(Temperature-dependent sex determination,TSD),而且这种温度依赖型性别决定机制只出现在性别发育的某一特定时期。近年来,研究者们开始尝试用分子生物学手段来研究罗非鱼性别决定及分化机制,寻找影响性别决定的基因位点、研究位点之间的相互关系及其相互作用,以及外界因素是如何通过调控性别决定位点来影响鱼类性别分化的等。目前研究的主要功能基因有DMRT基因家族、DAX1、SHP、AMH、oP450arom等。最新研究结果表明,tDMRT1可作为尼罗罗非鱼精巢分化的分子标记。The research of chromosomal genetic sex determination of tilapia was carried out very early, and it is widely used in present productions to get all-male tilapias by crossing between species. However, the research of environmental factors on sex determination and differentiation started later. It was suggested that there exists temperature-dependent sex determination in tilapia, which appears at a specific period in developmental stages. In recent years, a lot of research have been conducted to find out the molecular mechanism of sex determination and differentiation in tilapia, as well as to search the sex determination loci, the relationship and reciprocities between loci and how would the environment factors affect sex determination and differentiation by controlling loci of sex. determination. Work was mainly focused on functional genes such as DMRT family, DAX1, SHPS, AMH, oP450arom and so forth. Recent results suggests that tDMRT1 is a superior testicular differentiation marker in tilapia.

关 键 词：罗非鱼 染色体遗传型性别决定 温度依赖型性别决定 

分 类 号：Q959[生物学—动物学]