基于金纳米棒的生物检测、细胞成像和癌症的光热治疗  

Bio-Detection,Cellular Imaging and Cancer Photothermal Therapy Based on Gold Nanorods

作　　者：马占芳[1] 田乐[1] 邸静[1] 丁腾[1] 

机构地区：[1]首都师范大学化学系,北京100037

出　　处：《化学进展》2009年第1期134-142,共9页Progress in Chemistry

基　　金：北京市教育委员会科技计划项目(No.KM200810028010)资助

摘　　要：由于金纳米棒颗粒独特的可调的表面等离子共振特性,使得金纳米棒颗粒在纳米复合材料和功能化纳米器件的构建、纳米生物技术、生物医学等领域具有广泛而重要的应用前景。本文综述了金纳米棒颗粒的生物检测、细胞成像和癌症的光热治疗方面的最新研究进展,并介绍了金纳米棒颗粒的光学性质和金纳米棒颗粒和几种主要的表面修饰方法,对金纳米棒颗粒在生物应用过程中存在的主要问题进行了讨论。Due to unique and tunable surface plsmon resonance properties, gold nanorods have widely potential and important applications, i. e., fabrications of nanocomposites, nanodevices, nanobiotechnology, and biomedicine. Gold nanorods, therefore, have been attracted much attention. The latest advances on the applications of gold nanorods involving biological detection, cellular imaging, and cancer photothermal therapy are reviewed in this paper. Meanwhile the optical properties and several main approaches of surface modification of gold nanorods are also introduced. In addition the main issues existing in the biological applications are discussed.

关 键 词：金纳米棒 分子检测 细胞成像 癌症的光热治疗 

分 类 号：O614.123[理学—无机化学] O648.1[理学—化学]