酚妥拉明联合多巴胺治疗肾综合征出血热回顾性配对研究  

A Paired Retrospective Stdy of the Effects of Phentolamine Combined with Dopamine on Hemorrhagic Fever with Renal Syndrome

作　　者：熊良仕[1] 王进[1] 陈志冰[1] 赵仕弟[1] 梅小平[1] 

机构地区：[1]川北医学院附属医院传染科,南充637000

出　　处：《重庆医学》1998年第2期83-84,共2页Chongqing medicine

摘　　要：为提高肾综合征出血热（HFRS）治疗的存活率，选用中、重、危重型病例68例，1：1配对观察酚妥拉明、多巴胺联合治疗对HFRS急性肾功衰的疗效。结果：治疗组尽量增加显著高于对照组（P＜0．01）；少原期持续时向2.06±0．85天显著短于对照组3．58±1．27天；病死率治疗组为2.9％，对照组26．4％，两组比较有极显著性差异（P＜0．01）。以上结果表明：酚妥拉明联合多巴胺治疗能显著扩张肺、肾血管，改善微循环，增加血流量，提高肾综合征出血热治疗的存活率。To improve the srvival rate of hemorrhagic fever with renal syndrome (HFRS), thirty-four patients with acute renal failure as trial group were treated by phentolawhne combined with dopahane, whereas thirty-four patients as control group were treated by routine method. The results showed that the amount of daily urine in trial group was much higher than that in control group. The mean oliguric stagess were 2. o6fO. 85 days in tria1 group and 3. 58±1. 27 days in control group (P <0.01),respecfively. The fatality rates were 2. 9% (1/34) in trial group and 26.4% (9/34) in control group (P＜0.01).These data suggest that phentolawhne combined with dopawhne can dilate the vessels of lung and kindney dramatically, alter whcrocirculation, and improve the survival rate of HFRS.

关 键 词：肾综合征出血热 酚妥拉明 多巴胺 药物疗法 

分 类 号：R512.805[医药卫生—内科学]