急性心肌梗死患者合并左心衰与肌钙蛋白I、肌红蛋白浓度的关系  

The Relationship between Left Heart Failure and Concentration of cTnI and Myoglobin in Acute Myocardial Infarction

作　　者：唐浩熙[1] 夏明凯[1] 李介华[1] 张小勇[1] 陆灶其[1] 梁大立[1] 李冬秀[1] 

机构地区：[1]暨南大学医学院第五附属医院/广东省清远市人民医院

出　　处：《中西医结合心脑血管病杂志》2009年第1期21-23,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：广东省清远市科技局计划项目(No.20041721)

摘　　要：目的探讨肌钙蛋白I(cTnI)、肌红蛋白(Mb)浓度与急性心肌梗死(AMI)合并左心衰的关系。为左心衰患者的临床诊断提供依据。方法AMI无合并心力衰竭组171例,于胸痛发作后3h抽静脉血3mL送检。AMI合并左心衰组127例,于胸痛发作后3h表现为有左心衰症状时抽静脉血3mL。采用全自动微粒子化学发光分析仪定量检测cTnI、Mb。结果AMI无合并心衰组cTnI的浓度为(16.71±14.19)μg/L,Mb的浓度为(522.22±392.22)μg/L。AMI患者cTnI于胸痛3h后随时间增加而逐步增高,有左心衰症状时cTnI的浓度为(29.08±21.97)μg/L,Mb的浓度为(1010.96±935.98)μg/L,两组比较有统计学意义(P<0.05)。结论AMI患者cTnI浓度与心肌梗死部位及面积大少有关,cTnI浓度的测定对AMI合并左心衰的诊治有较大意义。Objective To explore relationship between left heart failure and the troponin Ⅰ （cTnI）, myoglobin （Mb） concentration in patients （pts） with acute myocardial infarction（AMI）. Methods There were 171 pts with AMI without left heart failure,and 127 pts with AMI with left heart failure. The cTnI and Mb were examined. Results In control group,the concentration of cTnI was（16.71±14.19）μg/L and concentration of Mb was （522.22±392.22）μg/L. The cTnI was increased gradually in pts with left heart failure. The concentration of cTnI was （29. 084±21.97） μg/L,and the concentration of Mb was （1 010. 964±935.98）μg/L （P〈0. 05）, Conclusion The concentration of cTnI was related with location and size of the AMI. The cTnI was significant for diagnosis and treatment of pts with AMI and left heart failure.

关 键 词：急性心肌梗死 左心衰 肌钙蛋白I 肌红蛋白 

分 类 号：R541.6[医药卫生—心血管疾病] R256.2[医药卫生—内科学]