N-(取代苯基)马来海松酸酰亚胺的合成及表征  

Synthesis and Characterization of N-(Substituted phenyl)maleopimarimide

作　　者：伍勇[1,2] 饶小平[1] 王宗德[2] 宋湛谦 

机构地区：[1]中国林业科学研究院林产化学工业研究所国家林业局林产化工重点开放性实验室,江苏南京210042 [2]江西农业大学园林与艺术学院,江西南昌330045

出　　处：《精细化工》2009年第1期98-101,共4页Fine Chemicals

基　　金：国家林业局“林业公益性行业科研专项”(200704008)~~

摘　　要：松香树脂酸衍生物具有广泛的生物活性。该文以松香为原料，在催化剂对甲基苯磺酸作用下与马来酸酐经Diels—Alder反应制得马来海松酸；马来海松酸与取代苯胺采用一步法在N，N-二甲基甲酰胺（DMF）溶剂中，于155℃反应4h，合成了8个具有潜在生物活性的N-（取代苯基）马来海松酸酰亚胺化合物，产率为42．5％～84．8％；对产物结构进行了IR、^1HNMR、^13CNMR光谱表征确认。Pine resin acids have extensive bioactivities. In the presence of p-toluenesulfonic acid as catalyst, maleopimaric acid is synthesized by Diels-Alder reaction from rosin. With N, N- dimethylformamide （DMF） as solvent, eight N-（ substituted phenyl） maleopimarimide compounds with potential bioaetivities are synthesized from maleopimaric acid and substituted aniline by one-step reaction under 155 ℃ for 4 h. Yields of eight N-（ substituted phenyl）maleopimarimide compounds are 42.5% -84. 8%. Their structures were confirmed by IR, ^1HNMR and ^13CNMR spectroscopy.

关 键 词：取代苯胺 马来海松酸 酰亚胺 

分 类 号：TQ351[化学工程]