低剂量内分泌干扰物暴露的生物效应研究进展  

Research Advance in Biological Effect of Low Does Endocrine Disruptors Exposure

作　　者：杜源生[1] 蒋学武[1] 

机构地区：[1]汕头大学医学院第二附属医院小儿外科,广东汕头515041

出　　处：《环境与健康杂志》2009年第1期85-87,共3页Journal of Environment and Health

基　　金：国家自然科学基金资助项目(30571935)

摘　　要：低剂量内分泌干扰物是否会对人类健康产生不利影响一直是近十年来研究的热点。很多学者认为,低于无可见不良效应剂量的内分泌干扰物即可产生生物效应。笔者详细阐述了内分泌干扰物低剂量效应的概念及产生机制,并总结了儿童期(生长期)低剂量内分泌干扰物暴露引起的一些与疾病有关的生物效应及相关研究中存在的若干问题。Whether low dose of endocrine disruptors （EDs） have adverse effects on human health is a hot spot in recent ten years. Many researchers consider that EDs lower than non-observed adverse-effects level can produce biological effects. In this paper the author expatiated the concept and mechanism of low dose effect of EDs, summarized some noso-biological-effects of low dose EDs to children. At the same time, some arguments of this field were introduced.

关 键 词：内分泌干扰物 暴露 剂量-效应 

分 类 号：R994.6[医药卫生—毒理学]