我市635例药品不良反应报告分析  

Analysis of 635 ADR Cases:Status and Countermeasures

作　　者：王安虎[1] 

机构地区：[1]云南保山市食品药品检验所,保山市678000

出　　处：《中国药房》2009年第2期141-142,共2页China Pharmacy

摘　　要：目的:提高药品不良反应(ADR)监测水平,促进临床合理用药。方法:对我市2006～2007年收集到的ADR报告635例,就报告来源、年龄分布、给药途径、涉及药品、累及器官或系统及临床表现等进行统计、分析。结果:635例ADR报告中,涉及药品106余种,抗感染药及中药制剂出现ADR的几率较高;皮肤及其附件损害居多,为349例,全身症状其次,为257例;新的或严重的ADR较少。结论:ADR的发生与给药途径、用药频次相关,基层医疗机构报告中严重ADR较少,应加强ADR的监测工作。OBJECTIVE： To improve the monitoring on the adverse drug reactions （ADR） and promote the rational drug use in the clinic. METHODS： A total of 635 ADR cases collected in our institute during the period 2006--2007 were analyzed statistically in respect of the sources of ADR reports, distribution of age, route of administration, the drugs involved, the organs and systems involved and the clinical manifestations etc. RESULTS： Of the total 635 ADR cases, the drugs involved to- talled more than 106 kinds, with anti - infective drugs and Chinese herbal preparations showing the highest proportions. Lesions of skin and its appendants took the lead （349 cases）, followed by general symptoms （257 cases）. There were few new or serious ADR. CONCLUSION： The occurrence of ADR is related to the route of administration and DDDs. Serious ADR reports from primary level hospital were few. ADR monitoring work should be emphasized further.

关 键 词：药品不良反应 现状 分析 

分 类 号：R969.3[医药卫生—药理学]